Results 101 to 110 of about 75,070 (261)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Development of methods for the processing of mining images using genetic algorithms [PDF]
Acta Montanistica Slovaca, 2012 In this paper we describe the extension of system FOTOM capabilities with respect to segmentation of specific mining images.We focus on methods that are inherently resistant against noise present in experimental pit at VSB Technical University.
Radim Farana +3 more
doaj
Measurement Science Review, 2013 Automatic suspected lesion extraction is an important application in computer-aided diagnosis (CAD). In this paper, we propose a method to automatically extract the suspected parotid regions for clinical evaluation in head and neck CT images.
Wu T. Y., Lin S. F.
doaj +1 more source
Narrow Band Active Contour Attention Model for Medical Segmentation. [PDF]
Diagnostics (Basel), 2021 Le N +4 more
europepmc +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Semi-supervised COVID-19 volumetric pulmonary lesion estimation on CT images using probabilistic active contour and CNN segmentation. [PDF]
Biomed Signal Process Control, 2023 Rodriguez-Obregon DE +8 more
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Initial Geometrical Templates with Parameter Sets for Active Contour on Skin Cancer Boundary Segmentation. [PDF]
J Healthc Eng, 2021 Bumrungkun P, Chamnongthai K, Patchoo W.
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source