Results 111 to 120 of about 81,242 (307)
Novel Computerized Method for Measurement of Retinal Vessel Diameters
Biomedicines, 2017 Several clinical studies reveal the relationship between alterations in the topologies of the human retinal blood vessel, the outcrop and the disease evolution, such as diabetic retinopathy, hypertensive retinopathy, and macular degeneration. Indeed, the
Hichem Guedri +3 more
doaj +1 more source
Semantic, Automatic Image Annotation Based On Multi-Layered Active Contours and Decision Trees
, 2013 In this paper, we propose a new approach for automatic image annotation (AIA) in order to automatically and efficiently assign linguistic concepts to visual data such as digital images, based on both numeric and semantic features.
Olszewska, Joanna Isabelle
core
Region-based active contour JSEG fusion technique for skin lesion segmentation from dermoscopic images [PDF]
, 2019 Malignant melanoma is one of the most aggressive forms of skin cancer which must be necessary to be diagnosed at the initial stage for effective treatment.
Javed, Rabia +3 more
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Two-step active contour method based on gradient flow
, 2010 Purpose - Active contour can describe target's silhouette accurately and has been widely used in image segmentation and target tracking. Its main drawback is huge computation that is still not well resolved.
Fan BJ(范保杰) +2 more
core
A Charged Active Contour based on Electrostatics
, 2006 We propose a novel active contour model by incorporating particle based electrostatic interactions into the geometric active contour framework. The proposed active contour, embedded in level sets, propagates under the joint influence of a boundary ...
Yang, R +5 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source