Results 31 to 40 of about 42,917 (265)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Novel Global Energy and Local Energy-Based Legendre Polynomial Approximation for Image Segmentation

Journal of Function Spaces, 2020
Active contour model (ACM) is a powerful segmentation method based on differential equation. This paper proposes a novel adaptive ACM to segment those intensity inhomogeneity images.
Feng Hu, Mengyun Zhang, Bo Chen
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A Partition-Based Active Contour Model Incorporating Local Information for Image Segmentation

The Scientific World Journal, 2014
Active contour models are always designed on the assumption that images are approximated by regions with piecewise-constant intensities. This assumption, however, cannot be satisfied when describing intensity inhomogeneous images which frequently occur ...
Jiao Shi, Jiaji Wu, Anand Paul, Licheng Jiao, Maoguo Gong   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Improved Algorithm for Gradient Vector Flow Based Active Contour Model Using Global and Local Information

The Scientific World Journal, 2013
Active contour models are used to extract object boundary from digital image, but there is poor convergence for the targets with deep concavities. We proposed an improved approach based on existing gradient vector flow methods. Main contributions of this
Jianhui Zhao, Bingyu Chen, Mingui Sun, Wenyan Jia, Zhiyong Yuan   +4 more
doaj   +1 more source

Fuzzy Region-Based Active Contours Driven by Weighting Global and Local Fitting Energy

IEEE Access, 2019
Active contour model (ACM) has been a successful method for image segmentation. The existing ACMs poorly segment the images with intensity inhomogeneity or non-homogeneity, and the results highly depend on the initial position of the contour. To overcome
Jiangxiong Fang, Huaxiang Liu, Liting Zhang, Jun Liu, Hesheng Liu   +4 more
doaj   +1 more source

A shape constrained parametric active contour model for breast contour detection [PDF]

2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2012
Quantitative measures of breast morphology can help a breast cancer survivor to understand outcomes of reconstructive surgeries. One bottleneck of quantifying breast morphology is that there are only a few reliable automation algorithms for detecting the breast contour.
Juhun Lee, Gautam S. Muralidhar, Gregory P. Reece, Mia K. Markey   +3 more
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Quantitative Comparison of Deformable Models in Range Segmentation

Cybernetics and Information Technologies, 2015
In this paper we segment range images by applying three deformable models (the classical Active Contour, the adaptive active contour and the Level Set method). These three methods are used to segment images with planar and curved surface scenes. Then the
Amine Khaldi, Hayet Farida Merouani
doaj   +1 more source