Results 51 to 60 of about 44,169 (308)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A fast level set image segmentation driven by a new region descriptor

open access: yesIET Image Processing, 2021
In order to deal with the intensities inhomogeneities and to overcome the effect of different types of noise in the image segmentation process, we have formulated a new level set function to implement a fast and robust active contour model.
Abdelkader Birane, Latifa Hamami
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

ROAD EXTRACTION FROM HIGH RESOLUTION SATELLITE IMAGES [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2012
Roads are significant objects of an infrastructure and the extraction of roads from aerial and satellite images are important for different applications such as automated map generation and change detection.
M. Özkaya
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Robust Active Contour Model Guided by Local Binary Pattern Stopping Function

open access: yesCybernetics and Information Technologies, 2017
Edge based active contour models are adequate to some extent in segmenting images with intensity inhomogeneity but often fail when applied to images with poorly defined or noisy boundaries.
Azizi Abdallah   +2 more
doaj   +1 more source

Water flow based complex feature extraction

open access: yes, 2006
A new general framework for shape extraction is presented, based on the paradigm of water flow. The mechanism embodies the fluidity of water and hence can detect complex shapes.
Liu, Xin U.   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Comprehensive Active Contour Model

open access: yesInternational Journal of Computer Applications, 2012
Image segmentation is one of the substantial techniques in the field of image processing. It is excessively used in the field of medicine provides visual means for identification, inspection and tracking of diseases for surgical planning and simulation.
Bharat Raju Dandu, Abhinav Chopra
openaire   +1 more source

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