Results 71 to 80 of about 42,663 (265)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Context-Driven Active Contour (CDAC): A Novel Medical Image Segmentation Method Based on Active Contour and Contextual Understanding

Sensors
Lung diseases, including chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis, pose significant health challenges due to their high morbidity and mortality rates.
Suane Pires Pinheiro da Silva, Roberto Fernandes Ivo, Calleo Belo Barroso, João Carlos Nepomuceno Fernandes, Thiago Ferreira Portela, Aldísio Gonçalves Medeiros, Pedro Henrique F. de Sousa, Houbing Song, Pedro Pedrosa Rebouças Filho   +8 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

GC Snakes: An Efficient and Robust Segmentation Model for Hot Forging Images

Sensors
Machine vision is a desirable non-contact measurement method for hot forgings, as image segmentation has been a challenging issue in performance and robustness resulting from the diversity of working conditions for hot forgings. Thus, this paper proposes
Xiaoyu Pan, Delun Wang
doaj   +1 more source

Performance of active contour models in train rolling stock part segmentation on high-speed video data

Cogent Engineering, 2017
Rolling stock examination is performed to identify the defects during train movements at speeds
Ch. Raghava Prasad, P.V.V. Kishore
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Automated Ultrasound Object Segmentation Using Combinatorial Active Contour Method

Jurnal Ilmu Komputer dan Informasi
Active Contour (AC) is an algorithm widely used in segmentation for developing Computer-Aided Diagnosis (CAD) systems in ultrasound imaging. Existing AC models still retain an interactive nature.
Anan Nugroho, Budi Sunarko, Hari Wibawanto, Anggraini Mulwinda, Anas Fauzi, Dwi Oktaviyanti, Dina Wulung Savitri   +6 more
doaj   +1 more source