Results 61 to 70 of about 42,663 (265)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A Snake Model Driven by Dynamic Local Data
MathematicsThere are several drawbacks in the existing localization (active contour) models. Some models have poor capability of handling uneven illuminations and low contrasts, others are sensitive to initial condition, and there are still some models which can ...
Qiang Li, Ming Yang
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The multichannel integration active contour framework for crack detection
International Journal of Advanced Robotic Systems, 2019 Crack is one of the most important defects to evaluate the health of concrete buildings. Hence, accurate detection is of great significance for the infrastructure maintenance.
Xiaomin Xie +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Applying Evolution Strategies for Chest Radiographs Segmentation [PDF]
Computer Science Journal of Moldova, 2006 WSegmentation is one of the key areas in computer vision. Advanced techniques, such as active contour models and active shape models suffer from many drawbacks. An improvement of the two approaches, based in evolution strategies, is presented.
Oliviu Matei
doaj
IEEE Access, 2019 Glaucoma is an eye disease which is one of the most common causes of blindness. Accurate optic disc (OD) and optic cup (OC) segmentation play a critical role for detecting glaucoma. Considering that the existing approaches can't effectively integrate the
Yuan Gao +5 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
COMPARISON OF DIFFERENT SEGMENTATION ALGORITHMS FOR DERMOSCOPIC IMAGES [PDF]
ICTACT Journal on Image and Video Processing, 2015 This paper compares different algorithms for the segmentation of skin lesions in dermoscopic images. The basic segmentation algorithms compared are Thresholding techniques (Global and Adaptive), Region based techniques (K-means, Fuzzy C means ...
A.A. Haseena Thasneem +3 more
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In Situ 3D Segmentation of Individual Plant Leaves Using a RGB-D Camera for Agricultural Automation
Sensors, 2015 In this paper, we present a challenging task of 3D segmentation of individual plant leaves from occlusions in the complicated natural scene. Depth data of plant leaves is introduced to improve the robustness of plant leaf segmentation. The low cost RGB-D
Chunlei Xia +3 more
doaj +1 more source