Results 41 to 50 of about 42,917 (265)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Noise Image Segmentation Model with Adaptive Neighborhood Based on Gradient Information [PDF]
An improved active contour model is proposed to solve the problem that most of the existing segmentation model can not take into account the segmentation accuracy of the probability noise image and the inhomogeneous image.Firstly,the new neighborhood ...
LI Gang,LI Haifang,SHANG Fangxin,GUO Hao
doaj +1 more source
An Active Contour Model Guided by LBP Distributions [PDF]
The use of active contours for texture segmentation seems rather attractive in the recent research, indicating that such methodologies may provide more accurate results. In this paper, a novel model for texture segmentation is presented, combining advantages of the active contour approach with texture information acquired by the Local Binary Pattern ...
Savelonas, M.A. +3 more
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Comparison Between The Performance of Parametric Active Contour Models
Snakes, or active contours, are used extensively in computer vision and image processing applications, particularly to locate object boundaries. In this research, for the segmentation of anatomical structures in medical images three approaches were ...
F. A. Alwan
doaj
A Vessel Active Contour Model for Vascular Segmentation [PDF]
This paper proposes a vessel active contour model based on local intensity weighting and a vessel vector field. Firstly, the energy function we define is evaluated along the evolving curve instead of all image points, and the function value at each point on the curve is based on the interior and exterior weighted means in a local neighborhood of the ...
Yun Tian +7 more
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A fast level set image segmentation driven by a new region descriptor
In order to deal with the intensities inhomogeneities and to overcome the effect of different types of noise in the image segmentation process, we have formulated a new level set function to implement a fast and robust active contour model.
Abdelkader Birane, Latifa Hamami
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

