Results 111 to 120 of about 5,060,163 (327)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Tool for Semiautomatic Labeling of Moving Objects in Video Sequences: TSLAB
An advanced and user-friendly tool for fast labeling of moving objects captured with surveillance sensors is proposed, which is available to the public. This tool allows the creation of three kinds of labels: moving objects, shadows and occlusions. These
Carlos Cuevas +2 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
The recognition and modelling of a backbone and its deformity
In this article the authors present a method for the backbone recognition and modelling. The process of recognition combines some classical techniques (Hough transformation, GVF snakes) with some new (authors present a method for initial curvature ...
Ramūnas Markauskas +3 more
doaj +1 more source
Image Segmentation Using Active Contours with Hessian-Based Gradient Vector Flow External Force. [PDF]
Qian Q, Cheng K, Qian W, Deng Q, Wang Y.
europepmc +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Automated Spleen Injury Detection Using 3D Active Contours and Machine Learning. [PDF]
Wang J +4 more
europepmc +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Projecting Active Contours with Diminutive Sequence Optimality
Active contours are widely used in image segmentation. To cope with missing or misleading features in image frames taken in contexts such as spatial and surveillance, researchers have commence various ways to model the preceding of shapes and use the ...
D. Baswaraj +2 more
core
Activity recognition (AR) methods require the ability to identify activities of crucial parts in a human body. Body segmentation techniques employed in video-based AR methods outlines significance of areas (parts) in a human body image that are essential
Madallah Alruwaili +2 more
doaj +1 more source

