Results 161 to 170 of about 5,060,163 (327)

Surface Water Body Detection in High-Resolution TerraSAR-X Data using Active Contour Models

open access: yes, 2010
This paper presents the application of two different active contour models for the segmentation of high-resolution TerraSAR-X data. Both methods facilitate the detection of land-water-boundaries in semi-automated procedures and can be used to delineate ...
Hahmann, Thomas, Wessel, Birgit
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

On the Relationship between Parametric and Geometric Active Contours

open access: yes, 2000
Geometric active contours have many advantages over parametric active contours, such as computational simplicity and the ability to change curve topology during deformation. While many of the capabilities of the older parametric active contours have been
Anthony Yezzi, Jr., Chenyang Xu
core  

Topology and Shape Constraints on Parametric Active Contours [PDF]

open access: yes, 2000
In recent years, the field of active contour based image segmentation has seen the emergence of two competing approaches. The first and oldest approach represents active contours in an explicit (or parametric) manner corresponding to the Lagrangian ...
Johan Montagnat   +3 more
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Three-dimensional GPU-accelerated active contours for automated localization of cells in large images. [PDF]

open access: yesPLoS One, 2019
Lotfollahi M   +5 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Lymph node segmentation by dynamic programming and active contours. [PDF]

open access: yesMed Phys, 2018
Tan Y   +6 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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