Results 151 to 160 of about 5,060,163 (327)

SEGMENTATION OF SINGLE ORIENTED IMAGES WITH CAGE ACTIVE CONTOURS [PDF]

open access: yes, 2016
Image segmentation primarily based on parametrized active contours. Active contours are of geometric and parametric types. Geometric active contours are used for curve topologies and parametric active contours are used for set of discrete points ...
Rajitha, T.; HOD-ECE,Turbomachinery Institute of Tech. & Sci., A. P.,   +1 more
core  

Automatic Blob Detection Method for Cancerous Lesions in Unsupervised Breast Histology Images

open access: yesBioengineering
The early detection of cancerous lesions is a challenging task given the cancer biology and the variability in tissue characteristics, thus rendering medical image analysis tedious and time-inefficient. In the past, conventional computer-aided diagnosis (
Vincent Majanga   +3 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Feature extraction via heat flow analogy

open access: yes, 2009
Feature extraction is an important field of image processing and computer vision. Features can be classified as low-level and high-level. Low-level features do not give shape information of the objects, where the popular low-level feature ...
Direkoğlu, Cem
core  

An Unsupervised Computed Tomography Kidney Segmentation with Multi-Region Clustering and Adaptive Active Contours

open access: yesMathematics
Kidney segmentation from abdominal computed tomography (CT) images is essential for computer-aided kidney diagnosis, pathology detection, and surgical planning.
Jinmei He   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Segmentation of bone structures in Magnetic Resonance Images (MRI) for human hand skeletal kinematics modelling

open access: yes, 2011
Roboticists have shown a great interest in designing and building robotic hands, mainly because of the complex structure and high range of functionalities that the human hand has.
Rusu, Alexandru
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Shape Extraction Via Heat Flow Analogy

open access: yes, 2007
In this paper, we introduce a novel evolution-based segmentation algorithm by using the heat flow analogy, to gain practical advantage. The proposed algorithm consists of two parts.
Nixon, Mark S, Direkoglu, Cem
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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