Results 51 to 60 of about 6,760,865 (281)

A Lower-Bound Approach to Active and Passive Earth Pressure Problems

open access: yesSoils and Foundations, 1990
ABSTRACT Active and passive earth pressures acting on retaining walls are known to be a complicated function of many factors, for instance, the cohesion and friction angle of backfill material, wall friction, and geometries of wall and backfill. Conventional theories based on stability analysis, e.g., Coulomb and Rankine methods which are now quite ...
ARAI, KATSUHIKO, JINKI, RIE
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Study on critical buckling load calculation method of piles considering passive and active earth pressure

open access: yes, 2013
Different types of long slender pile shall buckle with weak soil and liquefied stratum surrounded. Different from considering single side earth pressure, it was suggested that the lateral earth pressure can be divided into two categories while buckling ...
Xu, Kai   +4 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Heliotropic dust rings for Earth climate engineering [PDF]

open access: yes, 2013
This paper examines the concept of a Sun-pointing elliptical Earth ring comprised of dust grains to offset global warming. A new family of non-Keplerian periodic orbits, under the effects of solar radiation pressure and the Earth's J(2) oblateness ...
Bewick, Russell   +4 more
core   +4 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Research on the calculation method for non-limited active earth pressure of the retaining structures under the influence of basement’s external wall

open access: yes工程科学与技术, 2016
:For research the relationship between pressure and displacement of retaining structure, a method for calculating the non-limited active earth pressure of retaining structures under the influence of the external wall of basement was proposed.
qiangyue
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Method for lateral forces in stability analysis of concave slopes in plan view

open access: yesYantu gongcheng xuebao, 2018
Although it is well known that the stability of concave slopes in plan view is better than that of straight slopes, it is difficult to accurately calculate the factor of safety of concave slopes because the lateral forces perpendicular to the sliding ...
LI Li 1, LIU Zi-ru 2
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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