Results 71 to 80 of about 610,277 (358)

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

A decentralized fault-tolerant control scheme based on Active Fault Diagnosis [PDF]

2016 IEEE 55th Conference on Decision and Control (CDC), 2016
This paper deals with a decentralized faulttolerant control methodology based on an Active Fault Diagnosis approach. The proposed technique addresses the important problem of monitoring interconnected Large-Scale Systems (LSS). The fault diagnosis approach is made of a passive set-based fault detection method and an active fault isolation technique ...
Raimondo, D. M., Boem, F., Gallo, A., PARISINI, Thomas   +3 more
openaire   +4 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Robust fault-tolerant control [PDF]

, 2004
There are two main approaches to fault-tolerant control: passive and active.This thesis presents both methods for passive and for active ...
Kanev, Stoyan Kamenov
core   +2 more sources

Interaction of piled foundation with a rupturing normal fault [PDF]

, 2013
Post-seismic observations in the 1999 Kocaeli earthquake in Turkey have indicated that piled foundations may be less suitable than stiff mat foundations in defending a structure against a major normal fault rupturing underneath.
A. TSATSIS, Abaqus, Ambraseys N. N., Bray J. D., G. GAZETAS, I. ANASTASOPOULOS, Imbsen &, Kawashima K., Loli M., R. KOURKOULIS, Scott R. F., Ulusay R., White R. J., Youd T. L.   +13 more
core   +3 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

FULL VEHICLE ACTIVE SUSPENSION: SENSOR FAULT DIAGNOSIS AND FAULT TOLERANCE

IFAC Proceedings Volumes, 2006
Abstract In this paper, sensor fault detection, identification and fault tolerance model-based approach is designed for a linear full vehicle's active suspension system. The approach uses a bank of reduced order sliding mode observers to generate residuals.
Abbas Chamseddine, Hassan Noura, Thibaut Raharijaona   +2 more
openaire   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Palaeoseismologic and geomorphic investigations along the middle portion of the Ovindoli-Pezza Fault (Central Italy)

Annals of Geophysics, 1996
his paper presents the results of a detailed investigation performed along the central part of the Ovindoli- Pezza Fault with the aim of improving our understanding of the seismic behaviour of this fault within Central Italy seismogenesis. Results of the
P. M. De Martini, D. Pantosti, G. D' Addezio   +2 more
doaj   +1 more source