Results 61 to 70 of about 3,335,956 (283)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Major Bifurcations, Slip Rates, and A Creeping Segment of Sumatran Fault Zone in Tarutung-Sarulla-Sipirok-Padangsidempuan, Central Sumatra, Indonesia

open access: yesIndonesian Journal on Geoscience, 2018
DOI: 10.17014/ijog.5.2.137-160A detailed active fault study in Tarutung-Sarulla-Sipirok-Padangsidempuan was conducted based on their tectonic-morphological features using SRTM-30, 3D-visualization, and LIDAR data, combined with field and shallow ...
Danny Hilman Natawidjaja
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

InSAR-Based Mapping to Support Decision-Making after an Earthquake

open access: yesRemote Sensing, 2018
It has long been recognized that earthquakes change the stress in the upper crust around the fault rupture and can influence the behaviour of neighbouring faults and volcanoes.
Marta Béjar-Pizarro   +11 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Damage Tolerant Active Contro l: Concept and State of the Art [PDF]

open access: yes, 2012
Damage tolerant active control is a new research area relating to fault tolerant control design applied to mechanical structures. It encompasses several techniques already used to design controllers and to detect and to diagnose faults, as well to ...
NOBREGA, Euripedes, MECHBAL, Nazih
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

The internal structure, mechanics, and fluid flow properties of low-angle normal faults a case study from the island of Elba, Italy [PDF]

open access: yes, 2009
Low-angle normal faults have been extensively documented in areas of regional extension, in both continental and oceanic lithosphere, but their existence as seismically active structures remains controversial.
Smith, Steven A. F., Smith, Steven A F
core  

Paleoseismic trenching on slip-partitioned surface ruptures associated with the 2016 Kumamoto earthquake

open access: yesSeismica
Surface ruptures appear over a wide area in addition to the primary fault during a Large earthquake like the 2016 Kumamoto earthquake. Although the displacement of such distributed surface ruptures is small, information on their paleo activities provides
Daisuke Ishimura   +5 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

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