Results 71 to 80 of about 34,009 (308)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Earthquake Probability Assessment for the Active Faults in Central Taiwan: A Case Study

Terrestrial, Atmospheric and Oceanic Sciences, 2016
Frequent high seismic activities occur in Taiwan due to fast plate motions. According to the historical records the most destructive earthquakes in Taiwan were caused mainly by inland active faults.
Yi-Rui Lee, Chin-Tung Cheng, Kuo-Shih Shao, Yi-Rung Chuang, Jyr-Ching Hu, Tzu-Hua Lai, Shih-Ting Lu   +6 more
doaj   +1 more source

Analysis of CO₂ leakage through "low-permeability" faults from natural reservoirs in the Colorado Plateau, southern Utah [PDF]

, 2004
The numerous CO2 reservoirs in the Colorado Plateau region of the United States are natural analogues for potential geologic CO2 sequestration repositories.
Kirchner, D., Kolesar, P.T., Heath, J., Williams, A.P., Shipton, Z.K., Evans, J.P.   +5 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Efficient Simulation of Structural Faults for the Reliability Evaluation at System-Level [PDF]

, 2010
In recent technology nodes, reliability is considered a part of the standard design ¿ow at all levels of embedded system design. While techniques that use only low-level models at gate- and register transfer-level offer high accuracy, they are too ...
Hatami, N., Stefano Di Carlo, Baranowski, R., Wunderlich, H. J., Wunderlich, H.J., Zoellin, C. G., Michael E. Imhof, Hans-Joachim Wunderlich, Di Carlo, Stefano, Nadereh Hatami, Zoellin, C.G., Rafal Baranowski, Kochte, M. A., Imhof, M. E., Imhof, M.E., Paolo Prinetto, Prinetto, Paolo Ernesto, Michael A. Kochte, Kochte, M.A., Christian G. Zoellin   +19 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Analysis of the Stress Field Around Concealed Active Fault From Minor Faults‐Slip Data Collected by Geological Survey: An Example in the 1984 Western Nagano Earthquake Region

Earth and Space Science
Earthquakes with magnitudes of 6–7 have been reported even in various active tectonic settings where fault deformation topography have not been detected.
N. Nishiyama, T. Nakajima, A. Goto, H. Hakoiwa, M. Nagata, K. Shimada, M. Niwa   +6 more
doaj   +1 more source

The use of Terrestrial Laser Scanning in characterizing active tectonic processes from postseismic slip to the long term growth of normal faults [PDF]

, 2012
This thesis investigates two main hypotheses regarding uncertainty in the measurement of paleoseismic offsets used to estimate fault activity and paleoearthquake magnitudes on normal faults: (1) That variations in fault geometry have a significant effect
WILKINSON, MAXWELL
core  

Scale-dependent influence of pre-existing basement shear zones on rift faulting : a case study from NE Brazil

, 2013
Rifting of continental crust initiates faults that are commonly influenced by pre-existing structures. We document newly identified faults cutting Precambrian units in the interior of the NE Brazilian margin to assess the effects of structural ...
Lunn, Rebecca, Pytharouli, Stella, Bezerra, Hilario, do Nascimento, Aderson, Shipton, Zoe, Soden, Aisling, Kirkpatrick, James   +6 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source