Results 71 to 80 of about 3,335,956 (283)

Detection of Diesel Engine Injector Faults Using Acoustic Emissions [PDF]

open access: yes
This study investigated the method of identifying injector faults in a JCB 444T2 diesel engine using acoustic emission (AE) technique. Different kinds of injector faults were seeded in the four-cylinder, four-stroke, and turbo-engine.
Gu, Fengshou   +3 more
core   +5 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Partitioning method for seismic impact zones of tunnels crossing active faults based on energy principle and its applications

open access: yesYantu gongcheng xuebao
In order to improve the seismic performance of tunnels crossing active faults, starting from the energy response of structures, the factor of fault misalignment is introduced, the theory for calculating the energy response of tunnels crossing active ...
CUI Guangyao 1, HE Ziyang 1, CHEN Qinlong 1, WANG Mingnian 2, WANG Daoyuan 3
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Localization of Quaternary slip rates in an active rift in 10(5) years: an example from central Greece constrained by U-234-Th-230 coral dates from uplifted paleoshorelines [PDF]

open access: yes, 2009
Mapping, dating, and modeling of paleoshorelines uplifted in the footwall of the 1981 Gulf of Corinth earthquake fault, Greece (Ms 6.9–6.7), are used to assess its slip rate history relative to other normal faults in the area and study strain ...
Wigley, T.   +34 more
core   +1 more source

A critical review of field relationships and gravitational origin of active normal faults in the Kashmir basin, NW Himalaya

open access: yesJournal of Asian Earth Sciences: X, 2020
Kashmir basin is a piggyback basin that has developed at the last stage of the ongoing collision between India and Eurasia, and it is ~4 Ma old and contains 1300 m thick blanket of Plio-Pleistocene to Holocene deposits. These unconsolidated sediments are
Shah Afroz Ahmad   +3 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

A SEISMOTECTONIC MAP OF EASTERN SIBERIA

open access: yesГеодинамика и тектонофизика, 2015
The paper reviews goals and objectives, stages and the content of seismotectonic studies conducted in Eastern Siberia. Such studies are based on a comprehensive analysis of geological and geophysical data and provide for establishing whether the local ...
Valery S. Imaev   +5 more
doaj   +1 more source

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