Results 71 to 80 of about 17,259 (265)

Partitioning method for seismic impact zones of tunnels crossing active faults based on energy principle and its applications

Yantu gongcheng xuebao
In order to improve the seismic performance of tunnels crossing active faults, starting from the energy response of structures, the factor of fault misalignment is introduced, the theory for calculating the energy response of tunnels crossing active ...
CUI Guangyao 1, HE Ziyang 1, CHEN Qinlong 1, WANG Mingnian 2, WANG Daoyuan 3
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

A critical review of field relationships and gravitational origin of active normal faults in the Kashmir basin, NW Himalaya

Journal of Asian Earth Sciences: X, 2020
Kashmir basin is a piggyback basin that has developed at the last stage of the ongoing collision between India and Eurasia, and it is ~4 Ma old and contains 1300 m thick blanket of Plio-Pleistocene to Holocene deposits. These unconsolidated sediments are
Shah Afroz Ahmad, Syaakiirroh Sahari, Asiya Qadir, Nurhafizah Abd Manan   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

A SEISMOTECTONIC MAP OF EASTERN SIBERIA

Геодинамика и тектонофизика, 2015
The paper reviews goals and objectives, stages and the content of seismotectonic studies conducted in Eastern Siberia. Such studies are based on a comprehensive analysis of geological and geophysical data and provide for establishing whether the local ...
Valery S. Imaev, Lyudmila P. Imaeva, Oleg P. Smekalin, Boris M. Koz’min, Nikolai N. Grib, Anatoly V. Chipizubov   +5 more
doaj   +1 more source

Ambient noise differential adjoint tomography reveals fluid-bearing rocks near active faults in Los Angeles. [PDF]

Nat Commun, 2023
Liu X, Beroza GC, Li H.
europepmc   +1 more source