Results 81 to 90 of about 3,335,956 (283)
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Earthquakes with magnitudes of 6–7 have been reported even in various active tectonic settings where fault deformation topography have not been detected.
N. Nishiyama +6 more
doaj +1 more source
ABOUT THE WAVE MECHANISM OF ACTIVATION OF FAULTS IN SEISMIC ZONES OF THE LITHOSPHERE IN MONGOLIA
The study is focused on earthquake migrations along active faults in seismic zones of Mongolia. The earthquake migrations are interpreted as a result of the influence of deformational waves.
M. G. Mel’nikov
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Ambient noise differential adjoint tomography reveals fluid-bearing rocks near active faults in Los Angeles. [PDF]
Liu X, Beroza GC, Li H.
europepmc +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Editorial: Active faults and earthquake due to continental deformation
Chuanyou Li +3 more
doaj +1 more source
Distributed Acoustic Sensing Based on Microtremor Survey Method for Near-Surface Active Faults Exploration: A Case Study in Datong Basin, China. [PDF]
Song A +5 more
europepmc +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source

