Results 101 to 110 of about 34,009 (308)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Ambient noise differential adjoint tomography reveals fluid-bearing rocks near active faults in Los Angeles. [PDF]
Nat Commun, 2023 Liu X, Beroza GC, Li H.
europepmc +1 more source
Structural evolution of the Nam Con Son Basin: quantitative fault analysis applied to a 3-simensional seismic dataset [PDF]
, 2007 The Nam Con Son Basin is one of several Tertiary rift basins located on the continental shelf, offshore Indochina. It has received relatively little attention until recently and remains a poorly understood sedimentary basin.
Pugh, Adam
core
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
The Time-Dependent Method for Probabilistic Fault Displacement Hazard Analysis (PFDHA-td)
BuildingsCoseismic surface displacement can cause major damage to buildings located on faults. Therefore, it is important to quantitatively evaluate the future surface displacement of active faults. The commonly used deterministic evaluation methods often tend to
Qingyun Zhou, Xiaoxiang Yuan
doaj +1 more source
Distributed Acoustic Sensing Based on Microtremor Survey Method for Near-Surface Active Faults Exploration: A Case Study in Datong Basin, China. [PDF]
Int J Environ Res Public Health, 2023 Song A +5 more
europepmc +1 more source
Geometry, evolution and scaling of fault relay zones in 3D using detailed observations from outcrops and 3D seismic data [PDF]
, 2011 A new surface attribute was developed during the course of the thesis, which enables fault-related deformation – specifically, the apparent dip of mapped horizons measured in a direction perpendicular to the average strike of a fault array (here termed ...
Long, Jonathan James +1 more
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source