Results 91 to 100 of about 3,618,931 (286)
In order to protect the power electronic equipment and make the output current amplitude of distributed generation (DG) maintain a stable value for different short-circuit faults, this paper proposed a current-limiting strategy based on proportional ...
Jie Gao, Xiaowei Wang, Fengfeng Yang
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Damage Tolerant Active Contro l: Concept and State of the Art [PDF]
Damage tolerant active control is a new research area relating to fault tolerant control design applied to mechanical structures. It encompasses several techniques already used to design controllers and to detect and to diagnose faults, as well to ...
NOBREGA, Euripedes, MECHBAL, Nazih
core
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
A Novel Discrete Resonant Control Method for Cascaded H-Bridge Rail Balancers
This paper presents the concept of an advanced rail balancer (ARB) for next-generation traction substations (TSSs), along with its control algorithm based on a novel advanced resonant controller.
Straka Milos +5 more
doaj +1 more source
The paper presents proposal of the 2nd-order universal frequency filter. The presented filter operates in the current-mode and it is designed in the single-ended and fully-differential form. Signal-flow graphs (SFG) method has been used in the proposal.
LANGHAMMER, L. +3 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Tertiary nitrification of wastewater in trickling filters [PDF]
This study was designed to investigate, at laboratory and pilot scale, the effects of various loading and climatic factors on the nitrification perfon-nance of four media, and to undertake a comparative assessment of the media.
Biddle, Jeremy R.
core +2 more sources
LCL Interface Filter Design for Shunt Active Power Filters
This paper is focused on finding the parameters of a second order interface filter connected between the power system and the shunt active filter based on switching frequency of the active filter.
DOBRICEANU, M. +3 more
doaj +1 more source

