Results 81 to 90 of about 740,418 (299)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Wavelength tuneable pulse monitoring using a Two-Photon-Absorption microcavity [PDF]
, 2007 Two Photon Absorption (TPA) is a non-linear optical-to-electrical conversion process that can be significantly enhanced by placing the active region within a resonance microcavity.
Barry, Liam P. +7 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Comparison of active and passive EMI filters to reduction conducted noise
ITM Web of Conferences, 2018 The article presents the results of experimental studies of passive and active EMI filters for reduction of conducted noise. Firstly, the article presents selected structures of passive filters that have been tested in terms of insertion loss parameter ...
Pasko Marian, Szymczak Marek
doaj +1 more source
Hybrid Filters To Damp Harmonic Resonance In Power Transmission Systems
Eletrônica de Potência, 2006 Problems related to harmonic propagation in transmission systems have been noticed in the last years. Passive filters, commonly used to attenuate noncharacteristic harmonics in HVDC systems, stay at risk of disconnection from the system due to ...
Lucas F. Encarnação +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Genetic and combinatorial algorithms for optimal sizing and placement of active power filters
International Journal of Applied Mathematics and Computer Science, 2015 The paper deals with cost effective compensator placement and sizing. It becomes one of the most important problems in contemporary electrical networks, in which voltage and current waveform distortions increase year-by-year reaching or even exceeding ...
Maciążek Marcin +2 more
doaj +1 more source
The Dynamic Tunability of Memristor-Based Active Filters. [PDF]
Micromachines (Basel), 2023 Marković I +2 more
europepmc +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source