Results 111 to 120 of about 753,133 (348)

Active Collaborative Filtering

open access: yes, 2012
Collaborative filtering (CF) allows the preferences of multiple users to be pooled to make recommendations regarding unseen products. We consider in this paper the problem of online and interactive CF: given the current ratings associated with a user, what queries (new ratings) would most improve the quality of the recommendations made?
Boutilier, Craig   +2 more
openaire   +2 more sources

Active Frequency Filters for Higher Frequencies [PDF]

open access: yes, 2014
Práce pojednává o syntéze a optimalizaci kmitočtových analogových filtrů s moderními aktivními prvky užitých pro vyšší frekvence. Práce je rozdělena do tří částí, první část se zabývá problematikou týkající se kombinované ARC struktury Leap-Frog.
Fröhlich, Lubomír
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Shunt active DC filter based on intelligence controller for HVDC link

open access: yesHigh Voltage, 2017
A shunt active DC filter (ADF) with current injection suppresses current harmonics from high-voltage DC (HVDC) transmission systems. This paper proposes an ADF based on artificial neural networks (ANNs). The ANNs are very generic, accurate and convenient
Seyedreza Aali
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Biological active groundwater filters: exploiting natural diversity [PDF]

open access: bronze, 2012
W.W.J.M. de Vet   +3 more
openalex   +1 more source

A Single-Ended and Fully-Differential Universal Current-Mode Frequency Filter with MO-CF and DACA Elements

open access: yesAdvances in Electrical and Computer Engineering, 2016
The paper presents proposal of the 2nd-order universal frequency filter. The presented filter operates in the current-mode and it is designed in the single-ended and fully-differential form. Signal-flow graphs (SFG) method has been used in the proposal.
LANGHAMMER, L.   +3 more
doaj   +1 more source

Active filters for power quality improvement [PDF]

open access: yes, 2001
This paper deals with problems related with harmonics in power system networks. Several international standards issued to control power quality problems are briefly described and some important methods to analyse electrical circuits with non-sinusoidal ...
Afonso, João L.   +2 more
core  

Broad Band Photometric Reverberation Mapping of NGC 4395

open access: yes, 2012
We present results of broad band photometric reverberation mapping (RM) to measure the radius of the broad line region, and subsequently the black hole mass (M$_{\rm BH}$), in the nearby, low luminosity active galactic nuclei (AGN) NGC 4395.
Abazajian   +27 more
core   +1 more source

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