Results 181 to 190 of about 222,051 (290)

Autoimmune receptor encephalitis in mice induced by active immunization with conformationally stabilized holoreceptors. [PDF]

Sci Transl Med, 2019
Jones BE, Tovar KR, Goehring A, Jalali-Yazdi F, Okada NJ, Gouaux E, Westbrook GL.   +6 more
europepmc   +1 more source

Robust Bioconjugated Antigens Induce Immune Responses Preventing Malaria Infection and its Transmission

Small, EarlyView.
Engineered malaria antigens enable in vivo bioconjugation to submicron biopolymer particles in E. coli. Two antigens are co‐tethered at high density and defined stoichiometry. The resulting thermostable particles elicit strong, durable antibody and T‐cell responses, conferring robust protection and blocking mosquito transmission.
Nivethika Sivakumaran, Yevel Flores‐Garcia, Chanel M. Naar, Shuxiong Chen, Mili Mehta, Fijs W. B. van Leeuwen, Abhai Tripathi, Rajagopal Murugan, Meta Roestenberg, Fidel Zavala, Bernd H. A. Rehm   +10 more
wiley   +1 more source

Corrigendum: Wastewater-based surveillance identifies start to the pediatric respiratory syncytial virus season in two cities in Ontario, Canada

Frontiers in Public Health
Elisabeth Mercier, Lakshmi Pisharody, Fiona Guy, Shen Wan, Nada Hegazy, Patrick M. D'Aoust, Md Pervez Kabir, Tram Bich Nguyen, Walaa Eid, Bart Harvey, Erin Rodenburg, Candy Rutherford, Alex E. Mackenzie, Alex E. Mackenzie, Jacqueline Willmore, Charles Hui, Charles Hui, Bosco Paes, Robert Delatolla, Nisha Thampi, Nisha Thampi   +20 more
doaj   +1 more source

Active immunization by COVID-19 mRNA vaccine results in rapid antibody response and virus reduction in breakthrough infection by Delta (B.1.617.2)

, 2021
Hirotsu Y, Tsutsui T, Kakizaki Y, Miyashita Y, Iwase F, Maejima M, Sugiura H, Mochizuki H, Omata M.   +8 more
europepmc   +1 more source

The Willowbrook Experiments [PDF]

, 1973
Diamond, Eugene F.
core   +1 more source

Development of a Novel Polyleucine‐Based Immunopotentiator for Subunit Vaccines Against Group A Streptococcus

Small, EarlyView.
Self‐assembling amphiphilic peptide L15K6 is used as a novel immunoadjuvant for the development of a Group A Streptococcus vaccine. Robust antigen‐specific IgG responses are generated and manage to kill isolated strains of Group A Streptococcus. Cellular and bulk RNA sequencing data reveals that L15K6 regulates immune responses potentially through TLR ...
Lantian Lu, Jazmina L. Gonzalez Cruz, Rabina Giri, Yuexiao Zhang, Sahra Bashiri, Leslie C. Domínguez Cadena, Shuhang Li, Zeinab G. Khalil, Waleed M. Hussein, Jingwen Wang, Jolynn Kiong, Xuehan Lu, Jiahui Zhang, Miao Lu, Wenbin Huang, Wei Yang Kong, Ummey Jannatun Nahar, Prashamsa Koirala, Zhong Guo, Patricia Walden, Antje Blumenthal, Jakob Begun, Kirill Alexandrov, Istvan Toth, Rachel J. Stephenson, Mariusz Skwarczynski   +25 more
wiley   +1 more source

Who Is the System? On the Externalisation and Depersonalisation of Responsibility for Abuse

Systems Research and Behavioral Science, EarlyView.
ABSTRACT This article examines the externalisation and depersonalisation of responsibility in the institutional communication of the Roman Catholic Church in the context of sexualised violence. Niklas Luhmann's theory of social systems is used to show how semantic constructions such as ‘systemic causes’ rhetorically blur responsibility and contribute ...
Thomas Kron
wiley   +1 more source

Nanobody–chlorin e6 conjugate for Nectin‐4‐mediated tumor targeting and enhanced photodynamic therapy

VIEW, EarlyView.
Nectin‐4 is frequently overexpressed in solid tumors, yet many PDT photosensitizers show poor water solubility and nonspecific uptake. A Nectin‐4‐targeted nanobody–chlorin e6 conjugate (NPC) improves aqueous solubility and selectively accumulates in Nectin‐4‐positive tumor cells.
Haodian Wan, Tao Ye, Yawei Bi, Jiayu Zhang, Wei Wu, Aochi Liu, Li Sun, Jie Lin, Ningli Chai, Manjie Zhang, Jian Ma   +10 more
wiley   +1 more source

KD-409, a Respiratory Syncytial Virus FG Chimeric Protein without the CX3C Chemokine Motif, Is an Efficient Respiratory Syncytial Virus Vaccine Preparation for Passive and Active Immunization in Mice. [PDF]

Vaccines (Basel)
Yamaue R, Torikai M, Terashima M, Mori H.   +3 more
europepmc   +1 more source

Evaluation of antiviral - passive - active immunization ("sandwich") therapeutic strategy for functional cure of chronic hepatitis B in mice. [PDF]

EBioMedicine, 2019
Shi B, Wu Y, Wang C, Li X, Yu F, Wang B, Yang Z, Li J, Liang M, Wen Y, Ying T, Yuan Z.   +11 more
europepmc   +1 more source