Results 161 to 170 of about 117,260 (247)

Tofacitinib Regulates β‐Catenin Nuclear Translocation to Inhibit FLS Migration and Alleviate Clinical Symptoms of RA

iNew Medicine, EarlyView.
ABSTRACT Objective Tofacitinib is a Janus kinase (JAK) inhibitor approved for the treatment of moderate‐to‐severe rheumatoid arthritis (RA). However, its synovium‐related molecular mechanisms, particularly its regulatory effect on fibroblast‐like synoviocyte (FLS) migration, remain incompletely understood.
Shuqi Fang, Tianjing Zhang, Ling Hu, Ruijin Liu, Leyi Jia, Menglin Bai, Jiale Dong, Yuchen Zhao, Han Wang, Lei Zhang, Tao Li, Youcai Deng, Xianzheng Zhang, Lingling Zhang   +13 more
wiley   +1 more source

Corrigendum: Early active immunization with Aβ_3-10-KLH vaccine reduces tau phosphorylation in the hippocampus and protects cognition of mice. [PDF]

Neural Regen Res, 2020
europepmc   +1 more source

Specific peptide enrichment strategies for neuropsychiatric disorders: From material design to diagnostic applications

Interdisciplinary Medicine, EarlyView.
This review outlines specific peptide enrichment strategies, including metal, magnetic oxides, functional polymers, and antibody‐based approaches, and their mechanisms, highlighting applications in biomarker discovery for major neurological and psychiatric disorders.
Xue Zhang, Yejiao Shi, Minghui Guo, Yang Huang, Yirong Wang, Leping Huang, Helena S. Azevedo, Honggang Hu, Xin Dong   +8 more
wiley   +1 more source

Vaccine against PCSK9: the natural strategy from passive to active immunization for the prevention of atherosclerosis. [PDF]

J Thorac Dis, 2017
Civeira F, Jarauta E.
europepmc   +1 more source

Preliminary Development and Assessment of a Multiplex Assay for Human Papillomavirus Antibody Detection Using Commercial L1 Proteins

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed and assessed a new multiplex assay for the simultaneous detection of antibodies against multiple Human Papillomavirus (HPV) types. Using recombinant L1 protein, the assay quantifies IgG and IgA responses in human plasma, enabling comprehensive immune profiling across multiple high‐risk cancer‐associated HPV genotypes. This approach
Arash Aslanabadi, Maryam Karimi, Laura Powell, Lisa Schumaker, Ashley Shutt, Mahsa Hojabri, Rahim Abbasi, Søren M. Bentzen, Kevin J. Cullen, Trevor A. Crowell, Rebecca G. Nowak, Mohammad M. Sajadi   +11 more
wiley   +1 more source

Student Anxiety and Stress Related to Needlestick/Sharps Injuries in Dental Clinics

Journal of Dental Education, EarlyView.
ABSTRACT Purpose/Objective This study explored how the threat of needlestick/sharps injuries affects stress and anxiety among dental, dental hygiene, and dental assisting students in accredited US programs. It also aimed to identify contributing factors and assess potential educational interventions.
Lindsey C. Billing, Marisa A. Cornewell
wiley   +1 more source

Active Immunization Against hIAPP Oligomers Ameliorates the Diabetes- Associated Phenotype in a Transgenic Mice Model. [PDF]

Sci Rep, 2017
Bram Y, Peled S, Brahmachari S, Harlev M, Gazit E.   +4 more
europepmc   +1 more source

The Enteric Nervous System: An Integrative Hub From Development to Systemic Physiology

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Unlike a static hardwired circuit, the ENS continuously remodels its transcriptional programs and synaptic connectivity in response to three ecological forces: microbial metabolites, immune cell signals and enteroendocrine cues. ABSTRACT The enteric nervous system (ENS) constitutes the largest and most functionally autonomous subdivision of the ...
Mario Cuchillo‐Hilario, Margarita Díaz‐Martínez, Mario Alberto Viazcan‐Carbajal, Victor David González‐Fernández   +3 more
wiley   +1 more source

Active immunization in patients transplanted for hepatitis B virus related liver diseases: A prospective study. [PDF]

PLoS One, 2017
Yang A, Guo Z, Ren Q, Wu L, Ma Y, Hu A, Wang D, Ye H, Zhu X, Ju W, He X.   +10 more
europepmc   +1 more source

Clinical progress note: Mumps

Journal of Hospital Medicine, EarlyView.
Abstract Mumps was a common childhood viral illness before the implementation of the measles, mumps, and rubella (MMR) vaccination in 1967. There was a significant decrease in mumps cases in the postvaccine era; however, there has been an increase in outbreaks in the United States over the past two decades.
Sarah Ludvigsen, Mati Segev
wiley   +1 more source