Results 61 to 70 of about 118,708 (290)

Anticipating HIV viral escape – resistance to active and passive immunization

, 2023
PURPOSE: Active and passive immunization strategies are challenged by the extraordinary diversity of HIV, and the need for high titers of neutralizing antibodies to confer protective immunity.
Williamson, Carolyn, Carolyn Williamson, Rebecca M. Lynch, Penny L. Moore, Lynch, Rebecca M, Moore, Penny L   +5 more
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

EAE induction in C57/BL6 mice by adoptive transfer of encephalitogenic cells (at-EAE) or active immunization (active EAE).

, 2013
Incidence in at-EAE mice (A) and active EAE mice (B) between day 7 and 15 after immunization or adoptive transfer. (A) at-EAE symptoms appeared on day 8 after immunization and the 100% of incidence is reached on day 14.
Tony Valente (292054), Beatriz Moreno (292062), Francesc Graus (292056), Francesco Mannara (292052), Albert Saiz (292059), Josep Saura (37563)   +5 more
core   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source

Active immunization of mice with an Abeta-Hsp70 vaccine [PDF]

, 2004
Heat-shock proteins are highly immunogenic. Complexed with an antigen, they act as adjuvants, inducing a humoral and cellular immune response against both the antigen and the chaperone.
Christen, P, Koller, M F, Mohajeri, M H, Wollmer, M A, Tracy, J, Roth Z'graggen, B V, Sandmeier, E, Moritz, E, Nitsch, R M, Huber, M   +9 more
core   +1 more source

ANALISIS KELENGKAPAN IMUNISASI DASAR DI WILAYAH KERJA PUSKESMAS LEMO KABUPATEN BARITO UTARA

Al-Ulum, 2020
Healthy behaviour is a proactive attitude to maintain and improve health, prevent the risk of disease, protect yourself from disease threats and play an active role in public health movement activities.
Achmad Rizal, Agus Jalpi
doaj   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source

The relationship between prevalence of active trachoma, water availability and its use in a Tanzanian village.

, 2006
This study aimed to establish the relationship between the prevalence of active trachoma in children, water availability and household water use in a village in Tanzania.
Kuper, Hannah, Mahande, Michael, Polack, Sarah, Solomon, Anthony W, Abuelo, Carolina, Mabey, David, Valdmanis, Vivian, Foster, Allen, Massae, Patrick A, Cameron, Ewen   +9 more
core   +1 more source

Immunization against active ghrelin using virus-like particles for obesity treatment. [PDF]

, 2013
Ghrelin is a gut hormone that stimulates food intake. In physiological conditions, ghrelin plasma levels rise with fasting and decrease after meals. Obese individuals have low fasting ghrelin levels that rise after food restriction, which is pointed out ...
Carreira, Marcos, Ribeiro, Andreia M, Roy, Polly, Andrade, Sara, Casanueva, Felipe F, Monteiro, Mariana P, Pinho, Filipa   +6 more
core   +1 more source