Results 111 to 120 of about 181,510 (310)

İBN SİNA'DA BEDENSİZ KALAN RUHLARIN FERDİYETLERİNİN KORUNUP KORUNMADIĞINA DAİR PROBLEM ÜZERİNE

open access: yesFelsefe Dünyası, 2009
İBN SİNA'DA BEDENSİZ KALAN RUHLARIN FERDİYETLERİNİN KORUNUP KORUNMADIĞINA DAİR PROBLEM ...
Eyüp Şahin
doaj  

An analysis of god's attributes "The Beneficent" and "The Merciful" with regard to the philosophy of islamic jurisprudence [PDF]

open access: yes, 2003
I would like to begin my presentation with the quotation of the first sentence of Shafii’s Trea-tise er-Risala, the first work which has been reached us until now, concerning foundation of Islamic jurisprudence. “Praise be to God gratitude for one of His
Dagci, Samil
core  

Ibn Bajja. Conjunction of [Active] intellect with man

open access: yesIslam in the modern world
This publication presents a translation of the work of the first major representative of the “Western” branch of Muslim philosophy (falsafa), the Arab-Spanish philosopher Abu Bakr ibn Bajja (lat. Avempace; d. 1139). This treatise, dating back to the last years of the philosopher’s life, was written as a message to his friend and follower, the vizier ...
openaire   +1 more source

NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement

open access: yesAdvanced Science, EarlyView.
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang   +8 more
wiley   +1 more source

Ibn Sina on Happiness [PDF]

open access: yesاخلاق وحیانی, 2016
For Ibn Sina, happiness is the highest thing that the alive creature endeavor to find it. According to his ontological and anthropological principles, he regards the reason as the basic substance of human being, which by communicating with the active ...
Ali Shirvani
doaj  

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

open access: yesAdvanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi   +10 more
wiley   +1 more source

Psychoanalysis and God: A Comparative Analysis of Jacques Lacan and John of the Cross [PDF]

open access: yes, 2012
The author makes the case that Lacan and John of the Cross, taken together, reveal the full spectrum of the human journey toward God. Lacan s psychoanalytic theory is a valuable resource for understanding the earlier stages of the comprehensive spiritual
Kepes, Jr., Ted
core   +1 more source

IgG‐Bridging–Seeded Synergistic Aggregation of SARS‐CoV‐2 Spikes Underlies Potent Neutralization by a Low‐Affinity Antibody

open access: yesAdvanced Science, EarlyView.
Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv   +29 more
wiley   +1 more source

Gut Bacterium Lysinibacillus Sphaericus Exacerbates Aspirin‐induced Intestinal Injury by Production of Carboxylesterase EstB

open access: yesAdvanced Science, EarlyView.
Schematic overview illustrating the detrimental role of gut microbiota in aspirin‐induced intestinal injury. L. sphaericus and its secreted carboxylesterase EstB are identified as key drivers that catalyze aspirin hydrolysis into salicylic acid, thereby exacerbating intestinal injury. Inhibition of EstB by the dietary compound flavanomarein effectively
Zeyu Zhao   +13 more
wiley   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

open access: yesAdvanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu   +25 more
wiley   +1 more source

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