Results 71 to 80 of about 12,455,841 (338)

How to Help Young Children Ask Better Questions?

open access: yesFrontiers in Psychology, 2021
In this paper, we investigate the informativeness of 4- to 6-year-old (N = 125) children’s questions using a combined qualitative and quantitative approach.
Azzurra Ruggeri   +4 more
doaj   +1 more source

Active Discriminative Text Representation Learning

open access: yes, 2016
We propose a new active learning (AL) method for text classification with convolutional neural networks (CNNs). In AL, one selects the instances to be manually labeled with the aim of maximizing model performance with minimal effort.
Lease, Matthew   +2 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Cross-cultural adaptation and validation of a Resistance Training Skill Battery for use in Chinese-speaking adolescents [PDF]

open access: yesPeerJ
Purpose Although the Resistance Training Skills Battery (RTSB) is a well-established instrument for assessing resistance training (RT) skill competency in Western populations, its applicability to Chinese adolescents remains unvalidated. This study aimed
Xiaolu Zha   +3 more
doaj   +2 more sources

Associations of muscle-strengthening exercise with overweight, obesity, and depressive symptoms in adolescents: Findings from 2019 Youth Risk Behavior Surveillance system

open access: yesFrontiers in Psychology, 2022
BackgroundPrevious studies have focused on the opposite relation between muscle strength, obesity, and depression in adults. Moreover, the evidence has indicated that obesity and depression in adults might be significantly decreased with Muscle Strength ...
Jizu Shi   +5 more
doaj   +1 more source

Barriers and Facilitators to the Learning and Acquisition of Research Competencies among Nursing Students through Active Methodologies: A Qualitative Study Using Reflective Writing [PDF]

open access: gold, 2023
Juan Francisco Velarde‐García   +7 more
openalex   +1 more source

Active Learning with Expert Advice [PDF]

open access: yes, 2013
Conventional learning with expert advice methods assumes a learner is always receiving the outcome (e.g., class labels) of every incoming training instance at the end of each trial. In real applications, acquiring the outcome from oracle can be costly or
Hoi, Steven   +2 more
core   +3 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Active learning methods used in nursing education [PDF]

open access: yesJournal of Pedagogical Research, 2019
In recent years; expectations, personality traits and learning styles vary between generations as a result of the changes in traditional lifestyle and the development of technology.
Ilkay Culha
doaj   +1 more source

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