Results 61 to 70 of about 578,053 (267)
CoRR, 2019 An artificial neuron is modelled as a weighted summation followed by an activation function which determines its output. A wide variety of activation functions such as rectified linear units (ReLU), leaky-ReLU, Swish, MISH, etc. have been explored in the literature.
Fayyaz ul Amir Afsar Minhas, Amina Asif
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Massive hemotransfusion in patients with critical blood loss [PDF]
PharmaciaTransfusion medicine has undergone a long historical evolution—from early attempts at animal-to-animal transfusion through animal-to-human procedures to successful human-to-human transfusions following the discovery of blood groups.
Maria Hristova Savcheva +19 more
doaj +3 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Scandinavian Journal of Disability ResearchThe aim of this study was to evaluate the impact of the four-day family-centered early intervention program Good Start on psychosocial constructs related to quality of life in parents of children with cerebral palsy.
Camilla Marie Larsen +4 more
doaj +1 more source
Optimism in Active Learning [PDF]
Computational Intelligence and Neuroscience, 2015 Active learning is the problem of interactively constructing the training set used in classification in order to reduce its size. It would ideally successively add the instance-label pair that decreases the classification error most. However, the effect of the addition of a pair is not known in advance.
Collet, Timothé, Pietquin, Olivier
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Pilot and Feasibility StudiesBackground TransformEd is an evidence-based program that targets initial teacher education to equip future teachers with innovative strategies that increase the health, wellbeing and education outcomes of school children.
Nicholas Riley +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source