Results 81 to 90 of about 12,455,841 (338)
Frontiers in Public Health, 2023 PurposePast studies have illustrated that the impact of sports participation on school-attending students’ well-being plays a significant role in the life course of adolescence, which is a golden period for developing sound psychological qualities ...
Tianzhuo Liu +5 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Frontiers in Sports and Active LivingIntroductionThis study set out to understand the association between teaching practices, teacher confidence, competence, self-efficacy, and the resulting student outcomes.MethodsData regarding teaching behaviours were collected via video recording and ...
Jin Yan +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Frontiers in Public Health, 2023 Background/ObjectivePhysical activity (PA) has been suggested to reduce screen time. This study aimed to explore the associations of physical education (PE), muscle-strengthening exercise (MSE), and sport participation with screen time.MethodsA multi ...
Xiaoqing Hu +7 more
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
ActuatorsThis study introduces a mechanical spectrum analyzer (MSA) inspired by the tonotopic organization of the basilar membrane (BM), designed to achieve two critical features. First, it replicates the traveling-wave behavior of the BM, characterized by energy
Shantanu H. Chavan +1 more
doaj +1 more source
Active Learning through Materials Development: A Project for the Advanced L2 Classroom [PDF]
Journal of the National Council of Less Commonly Taught Languages, 2008 Building on the notion of active learning, the assumption that students learn more when given opportunities to practice using their skills and to receive feedback on their performance, this article de-scribes a project undertaken in an Advanced (third ...
Katrina Daly Thompson
doaj
The future of technology enhanced active learning – a roadmap [PDF]
, 2008 The notion of active learning refers to the active involvement of learner in the learning process, capturing ideas of learning-by-doing and the fact that active participation and knowledge construction leads to deeper and more sustained learning ...
Kenny, Claire, Pahl, Claus
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source