Results 91 to 100 of about 2,377,587 (333)
Constraints on Natural MNS Parameters from |U_e3|
, 2003 The MNS matrix structure emerging as a result of recent neutrino measurements strongly suggests two large mixing angles (solar and atmospheric) and one small angle (|U_e3|
A. Aranda +40 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Synergetic effects of nano-boehmite and Y nano-zeolite on catalytic cracking of residue oil
Scientific ReportsBoehmite nanoparticles and NaY nanozeolite were synthesized by co-precipitation and hydrothermal methods, respectively, and characterized by XRD, FT-IR, TG-DTA, BET, and SEM techniques.
Ehsan Amini +5 more
doaj +1 more source
Bioenergetic-active hydrogel drives extracellular matrix synthesis for cartilage repair
Bioactive MaterialsBioenergy plays a fundamental role in cartilage anabolic processes such as extracellular matrix (ECM) synthesis. The design of bioenergetic-active materials for accelerating these processes provides a prospective strategy for cartilage repair.
Shangtong Jiang +12 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
The condition number for circulant networks [PDF]
, 2013 In this paper we prove that it is possible to use techniques specific to electromagnetic field synthesis in the study of some electrical circuits. The definition of a circulant network will be presented.
De Mey, Gilbert, Micu, Dan
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Invisible Z decay width bounds on active-sterile neutrino mixing in the (3+1) and (3+2) models
, 2007 In this work we consider the standard model extended with singlet sterile neutrinos with mass in the eV range and mixed with the active neutrinos. The active-sterile neutrino mixing renders new contributions to the invisible Z decay width which, in the ...
C. A. DE S. PIRES, Donini A., Yao W. M.
core +1 more source