Results 101 to 110 of about 2,377,587 (333)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Mueller-matrix ellipsometry studies of optically active structures in scarab beetles
EPJ Web of Conferences, 2010 The complexity of multilayers, photonic crystals, metamaterials and other artificial materials has promoted the use of spectroscopic, variable angle, generalized and Mueller-matrix ellipsometry.
Arwin H., Landin J., Järrendahl K.
doaj +1 more source
Automated Selection of Active Orbital Spaces
, 2016 One of the key challenges of quantum-chemical multi-configuration methods is the necessity to manually select orbitals for the active space. This selection requires both expertise and experience and can therefore impose severe limitations on the ...
Reiher, Markus, Stein, Christopher J.
core +2 more sources
Matrix Metalloproteinases Activities in Hypertension [PDF]
Hypertension, 2011 See related article, pp 123–130 One of the challenges in the development of molecular models of hypertension as a disease with end organ failure is the multifaceted nature of complications that accompany elevated blood pressure. Comorbidities can be detected even at early stages of hypertension and in patients with family history of hypertension even ...
openaire +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Integrated photonic programmable random matrix generator with minimal active components
npj NanophotonicsRandom matrices are fundamental in photonic computing because of their ability to model and enhance complex light interactions and signal processing capabilities.
Kevin Zelaya +2 more
doaj +1 more source
IEEE Access, 2017 Collaborative filtering algorithms, such as matrix factorization techniques, are recently gaining momentum due to their promising performance on recommender systems. However, most collaborative filtering algorithms suffer from data sparsity.
Xin Guan, Chang-Tsun Li, Yu Guan
doaj +1 more source
Two Zero Mass Matrices and Sterile Neutrinos
, 2012 Recent experimental data is indicative of the existence of sterile neutrinos. The minimal scheme that can account for the data and is consistent with cosmological observations is the 3+1 picture which consists of three predominantly active and one ...
Ghosh, Monojit +2 more
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source