Results 121 to 130 of about 905,153 (261)

Proximity-Induced Transfer of a Mass Tag Enables Direct Profiling of Active Matrix Metalloproteases. [PDF]

Angew Chem Int Ed Engl
Berthy L, Pasco U, Sejalon-Cipolla M, Bruyat P, Kaminska M, Malgorn C, Beau F, Osolin M, Novak M, Breznik B, Georgiadis D, Correia I, Groult E, Lequin O, Bregant S, Pers YM, Noel D, Thai R, Subra G, Cantel S, Devel L.   +20 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Functional drug screening of tumor organoids on an active-matrix digital microfluidic chip for cancer precision medicine. [PDF]

Microsyst Nanoeng
Sun R, Feng Z, Wu T, Ding F, Wu Y, Jin K, Li L, Jia Z, Gao R, Cong Y, Ho TY, Ma H, Hu S, Zhang L, Dong W.   +14 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Electron confinement-enhanced green InP-based quantum dots for active-matrix LEDs displays. [PDF]

Nat Commun
Guo N, He K, Li H, Li T, Li F, Feng J, He Z, Jiang L, Wu Y.   +8 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Full-Photolithographic High-Density Skin-Like Transistor Arrays for All-Organic Active-Matrix Displays. [PDF]

Nanomicro Lett
Xue P, Li J, Zhao X, Ni Y, Yu H, Liu X, Xiang B, Fu Y, Zhang J, Sun B, Xi P, Song X, Shi Y, Zhao G, Zhang M, Tong Y, Tang Q, Liu Y.   +17 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Flexible active-matrix micro-LED display with 1T-1FeMFET architecture featuring scaling-limit-free design. [PDF]

Nat Commun
Huang T, Yang G, Sang Y, Zhuo F, Liu M, Li G, Cheng H, Yu Z, Fu Z, Liu S, Shen H, Yu Z, Liu B, Wang X, Wu W, Shi R, Zhuang Z, Sun W.   +17 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source