Results 141 to 150 of about 7,971,620 (292)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Proximity-Induced Transfer of a Mass Tag Enables Direct Profiling of Active Matrix Metalloproteases. [PDF]

Angew Chem Int Ed Engl
Berthy L, Pasco U, Sejalon-Cipolla M, Bruyat P, Kaminska M, Malgorn C, Beau F, Osolin M, Novak M, Breznik B, Georgiadis D, Correia I, Groult E, Lequin O, Bregant S, Pers YM, Noel D, Thai R, Subra G, Cantel S, Devel L.   +20 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Functional drug screening of tumor organoids on an active-matrix digital microfluidic chip for cancer precision medicine. [PDF]

Microsyst Nanoeng
Sun R, Feng Z, Wu T, Ding F, Wu Y, Jin K, Li L, Jia Z, Gao R, Cong Y, Ho TY, Ma H, Hu S, Zhang L, Dong W.   +14 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Electron confinement-enhanced green InP-based quantum dots for active-matrix LEDs displays. [PDF]

Nat Commun
Guo N, He K, Li H, Li T, Li F, Feng J, He Z, Jiang L, Wu Y.   +8 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Full-Photolithographic High-Density Skin-Like Transistor Arrays for All-Organic Active-Matrix Displays. [PDF]

Nanomicro Lett
Xue P, Li J, Zhao X, Ni Y, Yu H, Liu X, Xiang B, Fu Y, Zhang J, Sun B, Xi P, Song X, Shi Y, Zhao G, Zhang M, Tong Y, Tang Q, Liu Y.   +17 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Flexible active-matrix micro-LED display with 1T-1FeMFET architecture featuring scaling-limit-free design. [PDF]

Nat Commun
Huang T, Yang G, Sang Y, Zhuo F, Liu M, Li G, Cheng H, Yu Z, Fu Z, Liu S, Shen H, Yu Z, Liu B, Wang X, Wu W, Shi R, Zhuang Z, Sun W.   +17 more
europepmc   +1 more source