Results 111 to 120 of about 6,656,778 (331)
Optimizing collective behavior of communicating active particles with machine learning
Machine Learning: Science and TechnologyBacteria and other self-propelling microorganisms produce and respond to signaling molecules to communicate with each other (quorum sensing) and to direct their collective behavior.
Jens Grauer +3 more
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
, 2022 Abstract The force-free nature of interfacial transport processes that are collectively terms as phoretic mechanisms (such as diffusiophoresis, electrophoresis, thermophoresis, etc) affords the possibility of designing self-propelled particles, e.g. Janus particles with built-in sources that arise from catalytic activity or light-induced
openaire +4 more sources
Species interconversion of deformable particles yields transient phase separation
New Journal of PhysicsWe consider a dense assembly of repulsive particles whose fluctuating sizes are subject to an energetic landscape that defines three species: two distinct states of particles with a finite size, and point particles as an intermediate state between the ...
Yiwei Zhang +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Rigid flocks, undulatory gaits, and chiral foldamers in a chemically active polymer
New Journal of PhysicsActive matter systems—such as a collection of active colloidal particles—operate far from equilibrium with complex inter-particle interactions that govern their collective dynamics. Predicting the collective dynamics of such systems may aid the design of
Arvin Gopal Subramaniam +3 more
doaj +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Dynamic density shaping of photokinetic E. coli
eLife, 2018 Many motile microorganisms react to environmental light cues with a variety of motility responses guiding cells towards better conditions for survival and growth.
Giacomo Frangipane +8 more
doaj +1 more source