Results 131 to 140 of about 5,634,404 (299)
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an9025855-6; Exhibited: Scottish Australia, Art Gallery of Ballarat, Mid July - late July ...
Macfarlane, J., active 1890-1898.
core
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
John McDouall Stuart planting the Union Jack on Central Mount Stuart, 1860 [picture] /
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an9025855 ...
Macfarlane, J., active 1890-1898.
core
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Blacks about to attack Leichardt's Camp, near the Gulf of Carpentaria, 1845 [picture] /
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an9025855-4; Exhibited: "Mr. Gilbert's Beautiful Parrakeet", National Library of Australia Visitor Centre, 22 June - 14 October 2007 ...
Macfarlane, J., active 1890-1898.
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Sturt's party threatened by blacks at the junction of the Murray and Darling, 1830 [picture] /
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an9025855 ...
Macfarlane, J., active 1890-1898.
core
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source

