Results 111 to 120 of about 540,685 (254)
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
, 2010 Pedagogical review, 26 pages, chapter to appear in "Rheology of Complex Fluids"
openaire +2 more sources
Optimizing collective behavior of communicating active particles with machine learning
Machine Learning: Science and TechnologyBacteria and other self-propelling microorganisms produce and respond to signaling molecules to communicate with each other (quorum sensing) and to direct their collective behavior.
Jens Grauer +3 more
doaj +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Dynamic density shaping of photokinetic E. coli
eLife, 2018 Many motile microorganisms react to environmental light cues with a variety of motility responses guiding cells towards better conditions for survival and growth.
Giacomo Frangipane +8 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Species interconversion of deformable particles yields transient phase separation
New Journal of PhysicsWe consider a dense assembly of repulsive particles whose fluctuating sizes are subject to an energetic landscape that defines three species: two distinct states of particles with a finite size, and point particles as an intermediate state between the ...
Yiwei Zhang +2 more
doaj +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Rigid flocks, undulatory gaits, and chiral foldamers in a chemically active polymer
New Journal of PhysicsActive matter systems—such as a collection of active colloidal particles—operate far from equilibrium with complex inter-particle interactions that govern their collective dynamics. Predicting the collective dynamics of such systems may aid the design of
Arvin Gopal Subramaniam +3 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source