Results 141 to 150 of about 540,685 (254)

Publisher Correction: Active matter in space. [PDF]

NPJ Microgravity, 2023
Volpe G, Bechinger C, Cichos F, Golestanian R, Löwen H, Sperl M, Volpe G.   +6 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Scaling Transition of Active Turbulence from Two to Three Dimensions

Advanced Science
Turbulent flows are observed in low‐Reynolds active fluids, which display similar phenomenology to the classical inertial turbulence but are of a different nature.
Da Wei, Yaochen Yang, Xuefeng Wei, Ramin Golestanian, Ming Li, Fanlong Meng, Yi Peng   +6 more
doaj   +1 more source

Synchronization in collectively moving inanimate and living active matter. [PDF]

Nat Commun, 2023
Riedl M, Mayer I, Merrin J, Sixt M, Hof B.   +4 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

From a microscopic inertial active matter model to the Schrödinger equation. [PDF]

Nat Commun, 2023
Te Vrugt M, Frohoff-Hülsmann T, Heifetz E, Thiele U, Wittkowski R.   +4 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Emergence of precursor instabilities in geo-processes: Insights from dense active matter. [PDF]

Heliyon, 2023
Regenauer-Lieb K, Hu M.
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Geometrical control of interface patterning underlies active matter invasion. [PDF]

Proc Natl Acad Sci U S A, 2023
Xu H, Nejad MR, Yeomans JM, Wu Y.
europepmc   +1 more source