Results 191 to 200 of about 6,656,778 (331)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Colloidal active matter

Europhysics News
In the last two decades, significant research progress has been made in artificially equipping colloidal particles with their own drive (“motor”). They are then called active particles. In this case, a single active colloid typically moves much faster and more dynamically than a passive one, which follows purely diffusive Brownian motion.
openaire   +1 more source

Approaching active matter from biophysics perspective. [PDF]

Biophys Physicobiol
Hayakawa M, Kawamata I.
europepmc   +1 more source

Collective pattern formations of animals in active matter physics. [PDF]

Biophys Physicobiol, 2021
Sugi T, Ito H, H Nagai K.
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Self-sustained frictional cooling in active matter. [PDF]

Nat Commun
Antonov AP, Musacchio M, Löwen H, Caprini L.   +3 more
europepmc   +1 more source

Programmed mechano-chemical coupling in reaction-diffusion active matter. [PDF]

Sci Adv, 2021
Senoussi A, Galas JC, Estevez-Torres A.
europepmc   +1 more source

A unified theory of emergent equilibrium phenomena in active and passive matter

, 2022
Venkat Venkatasubramanian, Abhishek Sivaram, Laya Das   +2 more
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Phases of active matter in two dimensions [PDF]

, 2018
Leticia F. Cugliandolo, Giuseppe Gonnella   +1 more
openalex   +1 more source