Results 41 to 50 of about 58,854 (258)
Active Optics and Aberration Correction Technology for Sparse Aperture Segmented Mirrors
Active optics and aberration correction techniques for sparse aperture segmented mirrors are studied. A finite element model of the sparse aperture segmented mirror was established, and a multi-aperture aberration polynomial was derived. According to the
Benlei Zhang +3 more
doaj +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The road to atomically thin metasurface optics
The development of flat optics has taken the world by storm. The initial mission was to try and replace conventional optical elements by thinner, lightweight equivalents.
Brongersma Mark L.
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Chirality invertible superstructure mediated active planar optics
Optically reconfigurable elements are in demand for future applications. The authors report on the use of chirality-invertible cholesteric liquid crystals to actively manipulate geometric phase and create switchable planar optics elements that perform a ...
Peng Chen +8 more
doaj +1 more source
Grouting slurry diffusion range based on active heating fiber optics monitoring
To quantify the diffusion range of slurry in grouting engineering, an active heating optical fiber (AHFO) monitoring method is proposed. The AHFO is arranged on the coal seam floor.
Lei Zhu +3 more
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source

