Results 51 to 60 of about 3,491,013 (300)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Optimising the NAOMI adaptive optics real-time control system [PDF]
This thesis describes the author's research in the field of Real-Time Control (RTC) for Adaptive Optics (AO) instrumentation. The research encompasses experiences and knowledge gained working in the area of RTC on astronomical instrumentation projects ...
Goodsell, S. J., Goodsell, S J
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Micro-Deformable Mirror: a low cost technology for cryogenic active and adaptive optics [PDF]
Electrostatically operated bi-directional deflecting silicon membranes can be created using bulk micromachining techniques. The 19-channel Micro-Deformable Mirror, potential candidate for space Active and Adaptive Optics, was built by OKO Technologies ...
Bonicel, Sebastien Louis
core
Double-sided fresnel zone plates as high performance optics in X-ray microscopy [PDF]
X-ray microscopy describes a range of analytical techniques, specialized for the characterization of organic and inorganic samples using high energy photons.
Mohácsi, István
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Butterfly Optics Exceed the Theoretical Limits of Conventional Apposition Eyes [PDF]
Optical experiments on butterfly compound eyes show that they have angular sensitivities narrower than expected from conventional apposition eyes. This superior performance is explained by a theoretical model where the cone stalk is considered as a ...
Nilsson, D.-E., +3 more
core +2 more sources
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
The use of liquid crystal adaptive optics devices in astronomy [PDF]
Images obtained from large astronomical telescopes are distorted and blurred by the effects of the atmosphere. In order to compensate for this, an adaptive optics system can be incorporated downstream from the telescope focus.
Love, G.D, Love, Gordon D.
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source

