Results 61 to 70 of about 58,854 (258)

Changing University Students’ Alternative Conceptions of Optics by Active Learning

open access: yesCenter for Educational Policy Studies Journal, 2013
Active learning is individual and group participation in effective activities such as in-class observing, writing, experimenting, discussion, solving problems, and talking about to-be-learned topics.
Zalkida Hadžibegović, Josip Sliško
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Optical Activity of Chiral Excitons

open access: yesAdvanced Materials
AbstractRecent activity in the area of chiroptical phenomena has been focused on the connection between structural asymmetry, electron spin configuration and light/matter interactions in chiral semiconductors. In these systems, spin‐splitting phenomena emerge due to inversion symmetry breaking and the presence of extended electronic states, yet the ...
Peter C. Sercel   +4 more
openaire   +3 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Development of large aperture elements for active and adaptive optics

open access: yesEPJ Web of Conferences, 2013
Large-aperture elements for laser active and adaptive optics are investigated in collaboration within IOP AcSci CR, FEng CTU and 5M. A bimorph deformable mirror for high-power lasers based on a lightweight structure with a composite core is currently ...
Stranakova E.   +4 more
doaj   +1 more source

Multi-Scale CNN Based Garbage Detection of Airborne Hyperspectral Data

open access: yesIEEE Access, 2019
Garbage detection is important for environmental monitoring in large areas. However, the manual patrol is time-consuming and labor-intensive. This paper proposes a method for monitoring garbage distribution in large areas with airborne hyperspectral data.
Dan Zeng   +3 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Wavefront analysis of a focus-tunable lens with gravity compensation

open access: yesJPhys Photonics
The application of focus-tunable lenses (FTL) has significantly expanded in the field of photonics in the last decade, establishing these devices as fundamental optoelectronic components in most experimental setups.
E Pérez-Cabré   +3 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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