Results 81 to 90 of about 321,734 (315)

Active and Adaptive X-Ray Optics at Diamond Light Source [PDF]

, 2022
John P. Sutter, Simon G. Alcock, Ioana-Theodora Nistea, Hongchang Wang, Kawal Sawhney   +4 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Wavefront analysis of a focus-tunable lens with gravity compensation

JPhys Photonics
The application of focus-tunable lenses (FTL) has significantly expanded in the field of photonics in the last decade, establishing these devices as fundamental optoelectronic components in most experimental setups.
E Pérez-Cabré, F Cuéllar, L Clavé, M S Millán   +3 more
doaj   +1 more source

HSI-IPNet: Hyperspectral Imagery Inpainting by Deep Learning With Adaptive Spectral Extraction

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2020
Feature representation is the key to the hyperspectral images (HSI) inpainting. Existing works mainly focus on using spectral and temporal auxiliary images to inpainting the corrupted region, which were proved to be low robust for all bands missing and ...
Rong Wong, Zhijiang Zhang, Yueming Wang, Fansheng Chen, Dan Zeng   +4 more
doaj   +1 more source

Extraterrestrial applications of solar optics for interior illumination [PDF]

Solar optics is a terrestrial technology that has potential extraterrestrial applications. Active solar optics (ASO) and passive solar optics (PSO) are two approaches to the transmission of sunlight to remote interior spaces.
Eijadi, David A., Williams, Kyle D.
core   +1 more source

Optically Active Trimethylcvclopropanecarboxylic Acids

Agricultural and Biological Chemistry, 1973
Four optically active trimethylcyclopropanecarboxylic acids were prepared from chrysanthemic acids, and their absolute configurations were determined on the basis of chrysanthemic acids whose configuration were already known. Toxicities of several rethronyl esters towards housflies were compared with those of chrysanthemic acids and the cis-acids were ...
Katsuhide Okada, Keimei Fujimoto, Yoshitoshi Okuno, Masanao Matsui   +3 more
openaire   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Tunable and reconfigurable metasurfaces and metadevices

Opto-Electronic Advances, 2018
Metasurfaces, two-dimensional equivalents of metamaterials, are engineered surfaces consisting of deep subwavelength features that have full control of the electromagnetic waves.
Nemati Arash, Wang Qian, Hong Minghui, Teng Jinghua   +3 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source