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Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Comparing carbon emissions from oral tenofovir disoproxil fumarate/emtricitabine for preexposure prophylaxis and long-acting injectables for HIV prevention. [PDF]

AIDS
Rodrigues K, Bahrambegi R, Reid M.
europepmc   +1 more source

Multivariate evaluation of the effect of the particle size distribution of an Active Pharmaceutical Ingredient on the performance of a pharmaceutical drug product: a real-case study

Chemometrics and Intelligent Laboratory Systems, 2018
In the pharmaceutical field, and in particular for inhalation drug products based on Dry Powder Inhaler, the Active Pharmaceutical Ingredient particle size distribution is one of the key parameters to drive the final drug product performance.
Alessandro Cavecchi, Diego Copelli
exaly   +2 more sources

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Active pharmaceutical ingredient poly(ionic liquid)-based microneedles for the treatment of skin acne infection

Acta Biomaterialia, 2020
Feng Yan, Jiangna Guo, Hengqing Cui
exaly  

Life Cycle Analysis within Pharmaceutical Process Optimization and Intensification: Case Study of Active Pharmaceutical Ingredient Production

ChemSusChem, 2014
Dana Kralisch, Lioubov Kiwi-Minsker, Volker Hessel   +2 more
exaly  

Raman Mapping of Low-Content Active-Ingredient Pharmaceutical Formulations. Part II: Statistically Optimized Sampling for Detection of Less Than 1% of an Active Pharmaceutical Ingredient

Applied Spectroscopy, 2008
Slobodan Šašić, Mark Whitlock
exaly  

Advantages of Utilizing Population Balance Modeling of Crystallization Processes for Particle Size Distribution Prediction of an Active Pharmaceutical Ingredient

Processes, 2019
Tamar Rosenbaum
exaly  

Synthesis and molecular dynamics of double active pharmaceutical ingredient-benzalkonium ibuprofenate

Journal of Molecular Liquids, 2016
Vijisha K Rajan, Safna Hussan K P, M Shahin Thayyil   +2 more
exaly  

Experimental and density functional theory studies on benzalkonium ibuprofenate, a double active pharmaceutical ingredient

Computational Biology and Chemistry, 2018
Vijisha K Rajan, K Muraleedharan, M Shahin Thayyil   +2 more
exaly