Results 221 to 230 of about 3,921,277 (285)

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

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Active Pharmaceutical Ingredients

2004
INTRODUCTION Active Pharmaceutical Ingredients (APIs) play an important role in the drug product industry. The most obvious contribution is that the API is the active ingredient that makes a drug product effective and provides the pharmacological activity of any drug product or dosage form.
Lih-Yang Lin, Edward Cohen
  +4 more sources

Asymmetric Synthesis of Active Pharmaceutical Ingredients

Chemical Reviews, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Jonathan T Reeves, Chris H Senanayake, Jinhua J Song   +2 more
exaly   +3 more sources

Multivariate Evaluation of the Effect of the Particle Size Distribution of an Active Pharmaceutical Ingredient on the Performance of a Pharmaceutical Drug Product: A Real-Case Study

Chemometrics and Intelligent Laboratory Systems, 2018
In the pharmaceutical field, and in particular for inhalation drug products based on Dry Powder Inhaler, the Active Pharmaceutical Ingredient particle size distribution is one of the key parameters to drive the final drug product performance.
Alessandro Cavecchi, Diego Copelli
exaly   +2 more sources

Manufacturing Peptides as Active Pharmaceutical Ingredients

Future Medicinal Chemistry, 2009
Today, there are more than 40 peptides on the pharmaceutical world market and more than 100 in several clinical phases. Although in the past the pharmaceutical industries had reduced their interest in peptides research, in recent decades, they have rekindled their interest in peptides as a result of contemporary novel technological accomplishments ...
Aikaterini A, Zompra, Athanassios S, Galanis, Oleg, Werbitzky, Fernando, Albericio   +3 more
openaire   +2 more sources

Continuous Isolation of Active Pharmaceutical Ingredients

2020
In this chapter the essential underlying science and engineering of filtration, washing and drying are outlined as a basis for identifying best practice. Subsequently the available continuous process equipment variants used in the pharmaceutical and associated industry sectors are described and their potential fit into a pharmaceutical context is ...
Price, Chris John, Barton, Alastair, Coleman, Simon   +2 more
openaire   +2 more sources

Active Pharmaceutical Ingredients

2005
Introduction. Process Development. Technology Transfer. Plant Design & Construction. Regulatory Requirements. Process Validation. Quality Assurance and Control. Plant Operations. Materials Management.
openaire   +1 more source

Excipients and Active Pharmaceutical Ingredients

AAPS Advances in the Pharmaceutical Sciences Series, 2014
Raw materials in pediatric formulations such as excipients, food ingredients, and active pharmaceutical ingredients (APIs) have received significant attention from regulatory agencies worldwide in recent times due to safety concerns. Not all excipients and food ingredients are “inert” and have been shown to interfere with the growth and development ...
Mohammed M Alvi, Parnali Chatterjee
exaly   +2 more sources