Crystal structure of pirfenidone (5-methyl-1-phenyl-1H-pyridin-2-one): an active pharmaceutical ingredient (API) [PDF]
Acta Crystallographica Section E: Crystallographic Communications, 2019 The crystal structure of pirfenidone, C12H11NO [alternative name: 5-methyl-1-phenylpyridin-2(1H)-one], an active pharmaceutical ingredient (API) approved in Europe and Japan for the treatment of Idiopathic pulmonary fibrosis (IPF), is reported here for ...
Mauro Barbero +4 more
doaj +4 more sources
Active pharmaceutical ingredient (API) chemicals: a critical review of current biotechnological approaches. [PDF]
Bioengineered, 2022 The aim of this article was to generate a framework of bio-based economy by an effective utilization of biomass from the perspectives of agriculture for developing potential end bio-based products (e.g. pharmaceuticals, active pharmaceutical ingredients).
Kumar V +7 more
europepmc +5 more sources
Promoting local production and active pharmaceutical ingredient (API) industry in low and middle income countries (LMICs): impact on medicines access and policy [PDF]
Journal of Pharmaceutical Policy and PracticeThe success of universal coverage depends on ensuring that patients have access to medicine. Encouraging local production of medicines in developing countries can provide better access to medicines.
Muhammad Akhtar Abbas Khan, Asim Rauf
doaj +4 more sources
Syntheses of Cinacalcet: An Enantiopure Active Pharmaceutical Ingredient (API)
Synthesis, 2016 Cinacalcet hydrochloride is the only approved drug acting as calcimimetic, a new class of compds. used in the therapy of secondary hyperparathyroidism and parathyroid carcinoma. Several generic drug manufacturers and research groups from academia have reported alternative approaches to this mol., mainly from (R)-(+)-1-(1-naphthyl)ethylamine ...
Marta Barniol-Xicota +2 more
exaly +3 more sources
Anais da Academia Brasileira de Ciências, 2023 Active Pharmaceutical Ingredient (API) is any component of the final pharmaceutical product that serves as the active ingredient. The goal of the API Manufacturing is to produce APIs that are competitively priced and meet the quality standards with the ...
MARLON DANIEL L. TONINI +2 more
doaj +1 more source
Elastic and Ultradeformable Liposomes for Transdermal Delivery of Active Pharmaceutical Ingredients (APIs) [PDF]
International Journal of Molecular Sciences, 2021 Administration of active pharmaceutical ingredients (APIs) through the skin, by means of topical drug delivery systems, is an advanced therapeutic approach. As the skin is the largest organ of the human body, primarily acting as a natural protective barrier against permeation of xenobiotics, specific strategies to overcome this barrier are needed ...
Eliana B. Souto +5 more
openaire +3 more sources
Chemometrics-Assisted UV-Vis Spectrophotometry for Quality Control of Pharmaceuticals: A Review
Indonesian Journal of Chemistry, 2023 Spectroscopic method in the UV-Vis region is considered the most molecular spectrometric method for content determination of a single component. However, a lot of pharmaceutical dosage forms comprise two or more components which lead to peak overlapping.
Laela Hayu Nurani +6 more
doaj +1 more source
British Journal of Pharmacy, 2022 This work demonstrated the importance of pre-formulation studies and proposed a generalised scheme for excipient screening in the early stage of amorphous solid dispersion(ASD) system development by profiling the excipients’ capability to solubilise ...
Dijia Liu +3 more
doaj +1 more source
Health effects of exposure to active pharmaceutical ingredients (APIs) [PDF]
Occupational Medicine, 2003 Workers involved in the manufacture of pharmaceutical products are exposed in the course of their work to the active pharmaceutical ingredient (API) in the products. Such APIs are designed to produce biological change in the human body, which is an unacceptable outcome in the pharmaceutical worker.To review the evidence for the presence of the health ...
R J L, Heron, F C, Pickering
openaire +2 more sources
Monitoring of Pentoxifylline Thermal Behavior by Novel Simultaneous Laboratory Small and Wide X-Ray Scattering (SWAXS) and Differential Scanning Calorimetry (DSC). [PDF]
PLoS ONE, 2016 The thermal and structural evolutions associated to active pharmaceutical ingredient (API) purity are monitored using a laboratory instrument (S3-MicroCaliX) allowing simultaneous time-resolved X-ray scattering at both wide and small angles (SWAXS) as a ...
Aden Hodzic +3 more
doaj +1 more source