Results 221 to 230 of about 7,041 (257)

Ionic Liquids as Active Pharmaceutical Ingredients (APIs)

2021
The development of effective drug delivery systems for poorly water-soluble drugs remains a significant challenge for the pharmaceutical industry because of their limited solubility, bioavailability, permeability and stability and their polymorphic conversion.
Rahman Md Moshikur, Masahiro Goto
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Polymorphism and Crystallization of Active Pharmaceutical Ingredients (APIs)

Current Medicinal Chemistry, 2009
Active pharmaceutical ingredients (APIs), frequently delivered to the patient in the solid-state as part of an approved dosage form, can exist in such diverse solid forms as polymorphs, pseudopolymorphs, salts, co-crystals and amorphous solids. Various solid forms often display different mechanical, thermal, physical and chemical properties that can ...
Jie, Lu, Sohrab, Rohani
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Active pharmaceutical ingredients (APIs) in ionic liquids: An effective approach for API physiochemical parameter optimization

Drug Discovery Today, 2022
Ionic liquids (ILs) are widely used as solvents, co-solvents and permeation enhancers in the biomedical and pharmaceutical fields. There are many advantages to using active pharmaceutical ingredients (APIs) in the production of ILs for drug delivery, including the ability to tailor solubility, improve thermal stability, increase dissolution, regulate ...
Mayank, Handa, Waleed H, Almalki, Rahul, Shukla, Obaid, Afzal, Abdulmalik Saleh Alfawaz, Altamimi, Sarwar, Beg, Mahfoozur, Rahman   +6 more
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Susceptibility of phytoplankton to the increasing presence of active pharmaceutical ingredients (APIs) in the aquatic environment: A review

Aquatic Toxicology, 2021
Human and veterinary pharmaceuticals either in the form of un-metabolized, incompletely metabolized, and metabolized drugs are increasingly present in aquatic ecosystems. These active pharmaceutical ingredients from pharmaceutical industries, hospitals, agricultural, and domestic discharges find their way into water systems - where they adversely ...
Mathias Ahii Chia, Adriana Sturion Lorenzi, Ilu Ameh, Suleiman Dauda, Micheline Kézia Cordeiro-Araújo, Jerry Tersoo Agee, Ibrahim Yusuf Okpanachi, Abosede Taofikat Adesalu   +7 more
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Separation of Active Pharmaceutical Ingredients (APIs) from Excipients in Pharmaceutical Formulations

Crystal Growth & Design, 2015
The active pharmaceutical ingredient (API) may be physically separated from the excipients in a pharmaceutical formulation by making use of the difference in density of the API and that of the excipients. The API may then be fully characterized by standard techniques.
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active (pharmaceutical) ingredient (API)

2009
Pharmacologically active part(s) of a formulation; in case of a salt, the active ingredient should be understood to include both, the therapeutic moiety and the appended portion of the molecule; the maximum acceptable deviation in the a.i. content of a finished product must not exceed ±5% at the time of manufacture → see also drug, medicinal product.
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Production of active pharmaceutical ingredients (APIs) from lignin-derived phenol and catechol

Green Chemistry, 2021
Active pharmaceutical ingredients (APIs) constitute a significant and growing global market; renewables are an increasingly important source of their starting materials.
Jimin Park, Megan A. Kelly, Jason X. Kang, Siddarth S. Seemakurti, Jasmine L. Ramirez, Marta C. Hatzell, Carsten Sievers, Andreas S. Bommarius   +7 more
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ChemInform Abstract: Syntheses of Cinacalcet: An Enantiopure Active Pharmaceutical Ingredient (API)

ChemInform, 2016
AbstractReview: [64 refs.
Marta Barniol‐Xicota, Rosana Leiva, Carmen Escolano, Santiago Vazquez   +3 more
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Removal of API's (Active Pharmaceutical Ingredients) from Organic Solvents by Nanofiltration

Separation Science and Technology, 2007
Abstract The removal of 5 specific active pharmaceutical ingredients (API's) with molecular weight of 189, 313, 435, 531, and 721, respectively, from toluene, methylene chloride, and methanol was studied by using solvent resistant nanofiltration.
Jeroen Geens, Bruno De Witte, Bart Van der Bruggen   +2 more
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A Review on Synthesis and Biological Activities of Nitrosamine Impurities in Active Pharmaceutical Ingredients (APIs)

International Journal of Research and Scientific Innovation
Nitrosamine impurities are chemical compounds that can unintentionally form in active pharmaceutical ingredient during manufacturing or storage. Nitrosamine are carcinogenic and genotoxic. Nitrosamines are a group of nitroso compounds that can be formed when secondary or tertiary amine from API like-Lansoprazole, Dasatinib, Nilotinib or Oxybutynin ...
Pooja S Dalvi, Sharad S Sankhe
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