Results 61 to 70 of about 23,612 (262)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Feature Tracking Based on Line Segments With the Dynamic and Active-Pixel Vision Sensor (DAVIS)

open access: yesIEEE Access, 2019
As a novel vision sensor, the dynamic and active-pixel vision sensor (DAVIS) combines a standard camera and an asynchronous event-based sensor in the same pixel array.
Kaiyue Li   +5 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

A Fully Digital Indirect Time-of-Flight Image Sensor With Multi-Frame Integration and Time-Gated Single-Photon Counting Method

open access: yesIEEE Access
This paper presents an indirect time-of-flight (iToF) image sensor, based on a single-photon avalanche diode (SPAD) and a time-gated single-photon counting (TGSPC) method.
Byungchoul Park, Hyeon-June Kim
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Determining the Fixed Pattern Noise of a CMOS Sensor: Improving the Autonomous Star Trackers Sensibility

open access: yesJournal of Aerospace Technology and Management, 2013
http://dx.doi.org/10.5028/jatm.v5i2.206 Autonomous star trackers are optical-electronic devices used for attitude determination of artificial satellites, having as a reference for this computation the positions of stars.
Eduardo dos Santos Pereira
doaj  

Active pixel image sensor array for dual vision using large‐area bilayer WS2

open access: yesInfoMat
Transition metal dichalcogenides (TMDs) are a promising candidate for developing advanced sensors, particularly for day and night vision systems in vehicles, drones, and security surveillance.
Arindam Bala   +8 more
doaj   +1 more source

Studies for an upgrade of ALICE Inner Tracking System: Pixel chip characterization

open access: yesEPJ Web of Conferences, 2017
Inner Tracking System (ITS) of ALICE is used for vertex determination and tracking. Future heavy-ion program at the LHC aims to run with high luminosity.
Park Jonghan
doaj   +1 more source

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