Results 61 to 70 of about 23,612 (262)
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Feature Tracking Based on Line Segments With the Dynamic and Active-Pixel Vision Sensor (DAVIS)
As a novel vision sensor, the dynamic and active-pixel vision sensor (DAVIS) combines a standard camera and an asynchronous event-based sensor in the same pixel array.
Kaiyue Li +5 more
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
This paper presents an indirect time-of-flight (iToF) image sensor, based on a single-photon avalanche diode (SPAD) and a time-gated single-photon counting (TGSPC) method.
Byungchoul Park, Hyeon-June Kim
doaj +1 more source
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
http://dx.doi.org/10.5028/jatm.v5i2.206 Autonomous star trackers are optical-electronic devices used for attitude determination of artificial satellites, having as a reference for this computation the positions of stars.
Eduardo dos Santos Pereira
doaj
Active pixel image sensor array for dual vision using large‐area bilayer WS2
Transition metal dichalcogenides (TMDs) are a promising candidate for developing advanced sensors, particularly for day and night vision systems in vehicles, drones, and security surveillance.
Arindam Bala +8 more
doaj +1 more source
Studies for an upgrade of ALICE Inner Tracking System: Pixel chip characterization
Inner Tracking System (ITS) of ALICE is used for vertex determination and tracking. Future heavy-ion program at the LHC aims to run with high luminosity.
Park Jonghan
doaj +1 more source

