Results 41 to 50 of about 23,612 (262)

The DEPFET Sensor-Amplifier Structure: A Method to Beat 1/f Noise and Reach Sub-Electron Noise in Pixel Detectors

open access: yesSensors, 2016
Depleted field effect transistors (DEPFET) are used to achieve very low noise signal charge readout with sub-electron measurement precision. This is accomplished by repeatedly reading an identical charge, thereby suppressing not only the white serial ...
Gerhard Lutz   +4 more
doaj   +1 more source

Integrated High-Temporal-Resolution and High-Density Subretinal Prosthesis Using a Correlated Double-Sampling Technique

open access: yesSensors, 2023
This paper presents a 1600-pixel integrated neural stimulator with a correlated double-sampling readout (DSR) circuit for a subretinal prosthesis. The retinal stimulation chip inserted beneath the photoreceptor layer comprises an array of an active pixel
Hosung Kang, Jungyeon Kim, Jungsuk Kim
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

A Hydrogenated Amorphous Silicon Thin-Film Transistor Optical Pixel Sensor for Ameliorating Influences of Ambient Light and Reflected Light

open access: yesIEEE Journal of the Electron Devices Society, 2017
This paper proposes a hydrogenated amorphous silicon thin-film transistor-based (a-Si:H TFT) optical pixel sensor. The proposed optical sensor compensates for variations of ambient light using photo TFTs that incorporate with three primary color filters,
Chih-Lung Lin   +5 more
doaj   +1 more source

Hybrid Deblur Net: Deep Non-Uniform Deblurring With Event Camera

open access: yesIEEE Access, 2020
Despite CNN-based deblur models have shown their superiority when solving motion blurs, restoring a photorealistic image from severe motion blur remains an ill-posed problem due to the loss of temporal information and textures.
Limeng Zhang   +3 more
doaj   +1 more source

Optimization of Photoelectron In-Situ Sensing Device in FD-SOI

open access: yesIEEE Journal of the Electron Devices Society, 2021
This article presents the optimization of a one-transistor active pixel sensor (1T-APS), known as the photoelectron in-situ sensing device (PISD) built in a fully-depleted silicon-on-insulator (FD-SOI) substrate.
J. Liu   +6 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

a-IGZO 3T-2C Pixel Circuit-Based Active-Matrix Self-Capacitive Fingerprint Sensor Array for Full-Area Multi-Identity Recognition

open access: yesIEEE Journal of the Electron Devices Society
This study proposes an active-matrix self-capacitive touch-fingerprint sensor array using three standard staggered amorphous indium gallium zinc oxide (a-IGZO) thin-film transistors (TFTs) and two capacitors (3T-2C) pixel circuit architecture.
Zikang Mei   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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