Results 51 to 60 of about 23,612 (262)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Temperature Sensors Integrated into a CMOS Image Sensor

Proceedings, 2017
In this work, a novel approach is presented for measuring relative temperature variations inside the pixel array of a CMOS image sensor itself. This approach can give important information when compensation for dark (current) fixed pattern noise (FPN) is
Accel Abarca, Shuang Xie, Jules Markenhof, Albert Theuwissen   +3 more
doaj   +1 more source

Design of an Edge-Detection CMOS Image Sensor with Built-in Mask Circuits

Sensors, 2020
In this paper, we propose a complementary metal-oxide-semiconductor (CMOS) image sensor (CIS) that has built-in mask circuits to selectively capture either edge-detection images or normal 8-bit images for low-power computer vision applications. To detect
Minhyun Jin, Hyeonseob Noh, Minkyu Song, Soo Youn Kim   +3 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Cloud Classification in Wide-Swath Passive Sensor Images Aided by Narrow-Swath Active Sensor Data

Remote Sensing, 2018
It is a challenge to distinguish between different cloud types because of the complexity and diversity of cloud coverage, which is a significant clutter source that impacts on target detection and identification from the images of space-based infrared ...
Hongxia Wang, Xiaojian Xu
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

ARCADIA fully depleted CMOS MAPS development with LFoundry 110 nm CIS

Frontiers in Sensors
Fully depleted CMOS sensors represent a significant step forward in radiation detection, combining the advantages of monolithic active pixel sensors with the enhanced signal collection efficiency of depleted bulk materials.
Manuel Da Rocha Rolo, Attilio Andreazza, Giovanni Ambrosi, Fabrizio Alfonsi, Gabriele Balbi, Gian-Franco Dalla Betta, Tommaso Croci, Massimo Caccia, Davide Chiappara, Thomas Corradino, Stefano Durando, Davide Falchieri, Alessandro Gabrielli, Piero Giubilato, Sara Garbolino, Roberto Iuppa, Marco Mandurrino, Serena Mattiazzo, Coralie Neubüser, Lucio Pancheri, Devis Pantano, Andrea Paterno, Matteo Pezzoli, Pisana Placidi, Lodovico Ratti, Ester Ricci, Angelo Rivetti, Romualdo Santoro, Gianluca Traversi, Jeffery Wyss   +29 more
doaj   +1 more source

Mixed Event-Frame Vision System for Daytime Preceding Vehicle Taillight Signal Measurement Using Event-Based Neuromorphic Vision Sensor

Journal of Advanced Transportation, 2022
An important aspect of the perception system for intelligent vehicles is the detection and signal measurement of vehicle taillights. In this work, we present a novel vision-based measurement (VBM) system, using an event-based neuromorphic vision sensor ...
Zhengfa Liu, Guang Chen, Ya Wu, Jiatong Du, Jörg Conradt, Alois Knoll   +5 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source