Results 51 to 60 of about 140,341 (257)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

A Post-Contingency Power Flow Control Strategy for AC/DC Hybrid Power Grid Considering the Dynamic Electrothermal Effects of Transmission Lines

open access: yesIEEE Access, 2019
The blocking of large-capacity HVDC or the tripping of AC transmission lines by accident will cause power flow transfer sharply and increase the risk of cascading faults in AC/DC hybrid power grid.
Jian Hu   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Drivetrain torsional vibration analysis and mitigation of grid-forming DFIG-based wind turbine generators

open access: yesInternational Journal of Electrical Power & Energy Systems
Insufficient drivetrain damping can cause torsional vibrations of doubly-fed induction generator (DFIG)-based wind turbine generators (WTGs), affecting their stability and safety.
You Ying   +7 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Improvement method for grid-forming energy storage power angle stabilization in transient state based on power angle deviation feedback

open access: yes电力工程技术
For grid-forming energy storage integrated into power systems dominated by new energy,voltage drops in the grid are caused by the instability of new energy generation.
Yaning SUN   +5 more
doaj   +1 more source

Coordinated Active and Reactive Power Control of VSC-HVDC for Enhancing Static Voltage Stability in AC/DC Systems

open access: yesEnergies
When conducting research on the static voltage stability of AC/DC systems with voltage source converter-high voltage direct current (VSC-HVDC) transmission lines, the focus is often given to reactive power control, neglecting the potential from active ...
Jinpeng Guo   +5 more
doaj   +1 more source

A novel wind-storage flexible joint frequency regulation strategy considering participation coefficient of wind power and charge–discharge balance of energy storage [PDF]

open access: yesAIP Advances
This paper presents an innovative flexible frequency regulation strategy that synergistically integrates wind power and energy storage systems, aiming to enhance frequency control performance by balancing wind power participation with energy storage ...
Chang Ye   +6 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

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