Results 81 to 90 of about 129,704 (258)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Adaptive Control for Improved Virtual Synchronous Generator Under Imbalanced Grid Voltage

IEEE Open Journal of the Industrial Electronics Society
As renewable energy continues to grow, more inverter-based distributed generators are being integrated into power grids, in which virtual synchronous generator (VSG) is widely adopted to regulate system voltage and stabilize frequency.
Yangyang Chen, Wei Han, Youhao Hu, Yilin Zhang   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Frequency coordinated control and parameter optimization for photovoltaic–energy storage systems based on a GA-BP hybrid algorithm

Frontiers in Energy Research
IntroductionFrequency oscillations induced by stochastic disturbances pose significant challenges to grid-connected photovoltaic (PV) systems. This study proposes an adaptive optimization strategy for photovoltaic-energy storage systems (PV-ESS) based on
Runzhi Mu, Hongchun Shu, Hongchun Shu, Hongchun Shu, Hongchun Shu, Yuming Zhang, Xiongbiao Wan, Shunji Luo, Shunji Luo, Shunji Luo, Shunji Luo, Zichao Zhou, Guangxue Wang, Guangxue Wang, Guangxue Wang, Guangxue Wang, Shunguang Lei, Shunguang Lei, Shunguang Lei, Shunguang Lei   +19 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Multitime Scale Reactive Power and Voltage Optimal Regulation for Transmission Network With Wind Power Cluster Based on Model Predictive Control

International Transactions on Electrical Energy Systems
In order to solve the problem of voltage fluctuation caused by the grid integration of wind power cluster, a multitime scale reactive power and voltage optimal regulation method based on model predictive control (MPC) is proposed in this paper.
Hong Wang, Chao Yuan, Wen Gu, Chun Yang, Minhao Kong, Jian Yu   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Discrete Time Control Method for SVM Direct Active Power and Stator Flux Control of PMSG-Based Wind Turbine

Iranian Journal of Electrical and Electronic Engineering, 2021
This paper proposes a new method for direct control of active power and stator flux of permanent magnet synchronous generator (PMSG) used in the wind power generation system.
B. Mamipour Matanag, N. Rostami, S. Tohidi   +2 more
doaj  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source