Results 181 to 190 of about 10,165,445 (355)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

High-resolution Observations of a C9.3 White-light Flare and Its Impact on the Solar Photosphere

open access: yesThe Astrophysical Journal Letters
We present a detailed analysis of a C9.3 white-light flare using high-resolution observations from the New Vacuum Solar Telescope. The flare occurred near the eastern solar limb on 2023 September 11, within NOAA AR 13431, and produced beam electrons with
Zhe Xu   +6 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Mother’s Day Superstorms: Pre- and Post-storm Evolutionary Patterns of ARs 13664/8

open access: yesThe Astrophysical Journal
In the week including Mother’s Day 2024, active region (AR) 13664 became superactive when AR 13668 emerged nearby, causing multiple X-class flares and coronal mass ejections, and an increase in activity level similar to that inferred from geomagnetic ...
Mausumi Dikpati   +8 more
doaj   +1 more source

Stability of Active Constraints Enforcement in Sensitive Regions Defined by Point-Clouds for Robotic Surgical Procedures

open access: green, 2019
Theodora Kastritsi   +4 more
openalex   +2 more sources

An investigation of the causal relationship between sunspot groups and coronal mass ejections by determining source active regions

open access: gold, 2021
Abd-ur Raheem   +5 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy