Results 261 to 270 of about 190,143 (303)

Screening and characterization of a highly active chitosanase based on metagenomic technology

Journal of Molecular Catalysis B: Enzymatic, 2015
Abstract A metagenomic fosmid library containing 8 × 10 4 clones was constructed from a soil sample taken from the stacking place of shrimp and crab shells. 12 clones with chitosanase activity were screened using LB agar plates containing 0.12 wt.% chitosan.
Heng Li, Zhong Fei, Jinsong Gong, Tao Yang, Zhenghong Xu, Jinsong Shi   +5 more
openaire   +1 more source

Screening of anti-aging active ingredients and mechanism analysis based on molecular docking technology

China Journal of Chinese Materia Medica, 2016
Dampness evil is the source of all diseases, which is easy to cause disease and promote aging, while aging could also promote the occurence and development of diseases. In this paper, the relationship between the dampness evil and aging would be discussed, to find the anti-aging active ingredients in traditional Chinese medicine (TCM), and analyze the ...
Ran-Feng, Du, Xiao-Hua, Zhang, Xiao-Tong, Ye, Wen-Kang, Yu, Yun, Wang   +4 more
openaire   +2 more sources

Abstract 918: Development of a platform for programmable in vivo oncogene activation and screening using CRISPRa technology

Cancer Research, 2022
Abstract Conventional genetically engineered mouse models (GEMMs) are time consuming, laborious and offer limited spatio-temporal control. We have developed a streamlined platform for in vivo gene activation using CRISPR activation (CRISPRa) technology.
Fredrik Ivar Thege, Dhwani N. Rupani, Bhargavi B. Barathi, Anirban Maitra, Andrew D. Rhim, Sonja M. Wörmann   +5 more
openaire   +1 more source

Activity-based screening system for the discovery of neuraminidase inhibitors using protein chip technology

BioChip Journal, 2012
Infectious bacteria or viral strain often expresses a family of neuraminidases to invade human body through the respiratory system. A role of the neuraminidase is cleaving specific glycosidic linkages of neuraminic acids when the pathogens are attached to cellular surface of host organisms.
Chan-Won Park, In-Cheol Kang, Youngjin Choi   +2 more
openaire   +1 more source

Screening of active ingredients contained in natural products based on micro-fluidic chip technology

China Journal of Chinese Materia Medica, 2012
With the constant development of the drug screening technology, new screening methods and techniques have came to the fore, driving drug screening to grow rapidly and efficiently with a high throughput. Characterized by micro-scale analysis, high throughput, inheritability and good biocompatibility, the micro-fluidic analytical technology provides a ...
openaire   +1 more source

Application of network pharmacology and high through-put technology on active compounds screening from traditional Chinese medicine

China Journal of Chinese Materia Medica, 2012
Objective To solve the difficult in the active compounds screening from traditional Chinese medicines (TCM). Method According to preliminary lab results and related literature, systematic analysis of the high-throughput technology was made. Result Technologies of rapid preparation, high-throughput screening and biochip, together with the thought ...
Qingshan, Liu, Ziqian, Zhang, Liang, Fang, Yifan, Jiang, Xiaoying, Yin   +4 more
openaire   +3 more sources

Screening the active ingredients of plants via molecular docking technology and evaluating their ability to reduce skin photoaging

Biogerontology
The active ingredients of plants were screened by molecular docking technology and the result were verified. According to the verification results of molecular docking, the five active ingredients were combined in equal proportions to form a compound drug.
Shiqian, Zheng, Rongrong, Deng, Gengjiu, Huang, Zhiwen, Ou, Zhibin, Shen   +4 more
openaire   +2 more sources

Antioxidant Screening of Beverages using the Online HPLC–DPPH• Assay Incorporating Active Flow Technology Chromatography Columns

2014
The analysis and isolation of antioxidants from complex samples requires a separation step to fractionate the sample, followed by a means to measure the presence of the antioxidants. This can be conveniently achieved using liquid chromatography coupled with an on-line antioxidant assay.
Camenzuli, Michelle (R17159), Dennis, Gary R. (R7569), Ritchie, Harald J., Shalliker, Ross A. (R8557)   +3 more
openaire   +3 more sources

[Screening of active anti-myocardial ischemia components of Panax notoginseng based on molecular docking technology].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2020
The molecular docking technology was used in this study to virtually screen the active anti-myocardial ischemic components in Panax notoginseng, clarify the compositions of the anti-myocardial ischemic component unit and the basis for pharmacological activity of P.
Chuan-Yan, Lin, Chen-Zi, Li, Chang, Li, Liang, Feng, Xiao-Bin, Jia   +4 more
openaire   +1 more source

13.1: Invited Paper : Technological Evolution for Large Screen Size Active Matrix OLED Display

SID Symposium Digest of Technical Papers, 2007
Abstract Vacuum evaporation process with metal mask using LTPS (Low Temperature Poly Silicon TFT) backplane is well established OLED production process. However this technology is not applicable for large sized display like TV. Various technologies to break through this constraint have been proposed so far. In this paper pros and cons
Tetsuo Urabe, Tatsuya Sasaoka, Koichi Tatsuki, Jun Takaki   +3 more
openaire   +1 more source