Results 11 to 20 of about 1,610,463 (321)
The active site of aspartic proteinases [PDF]
The active site of the aspartic proteinase, endothiapepsin, has been defined by X‐ray analysis and restrained least‐squares refinement at 2.1 Å resolution with a crystallographic agreement value of 0.16. The environments of the two catalytically important aspartyl groups are remarkably similar and the contributions of the NH2‐ and COOH‐terminal domains
Laurence H. Pearl, Tom L. Blundell
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Active site-specific immunoassays [PDF]
This study describes a process by which serine proteases that contain an S-1 arginine subsite and active site histidine may be inactivated and subsequently quantitated using a combination of peptidyl chloromethylketone chemistry and immune recognition technology.
E. B. Williams+5 more
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Homogeneity of Supported Single‐Atom Active Sites Boosting the Selective Catalytic Transformations
Selective conversion of specific functional groups to desired products is highly important but still challenging in industrial catalytic processes. The adsorption state of surface species is the key factor in modulating the conversion of functional ...
Yujie Shi+5 more
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PROPERTIES OF THE ACTIVE SITE OF ENZYMES* [PDF]
Daniel E. Koshland
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Metagenomic characterization of sphingomyelinase C in the microbiome of humans and environments
Bacterial sphingomyelinases (SMases) hydrolyze sphingomyelin and play an important role in membrane dynamics and the host immune system. While the number of sequenced genomes and metagenomes is increasing, a limited number of experimentally validated ...
Jehyun Jeon+7 more
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Background The aims of this study were (i) to define the relationship between a physical reconditioning cycle using balance exercises and muscular-articular stress and the balance capabilities of sedentary older adults and (ii) to assess whether older ...
Pierre Louis Bernard+5 more
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Copper is the only metal that can convert CO2 into C2 and C2+ in electrocatalytic carbon dioxide reduction (CO2RR). However, the Faraday efficiency of CO2 conversion to C2 and C2+ products at high current densities is still low, which cannot meet the ...
Tianmi Tang, Zhenlu Wang, Jingqi Guan
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Mapping the Active Site of CD59 [PDF]
CD59 is a widely distributed membrane-bound inhibitor of the cytolytic membrane attack complex (MAC) of complement. This small (77 amino acid) glycoprotein is a member of the Ly6 superfamily of proteins and is important in protecting host cells from the lytic and proinflammatory activity of the MAC.
Yu, Jinghua+5 more
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Gasification under CO2–Steam Mixture: Kinetic Model Study Based on Shared Active Sites
In this work, char gasification of two coals (i.e., Shenfu bituminous coal and Zunyi anthracite) and a petroleum coke under a steam and CO2 mixture (steam/CO2 partial pressures, 0.025–0.075 MPa; total pressures, 0.100 MPa) and CO2/steam chemisorption of ...
Xia Liu+3 more
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Viral RNA-dependent RNA polymerases (RdRps) play a central role not only in viral replication, but also in the genetic evolution of viral RNAs. After binding to an RNA template and selecting 5′-triphosphate ribonucleosides, viral RdRps synthesize an RNA ...
Barbara Selisko+3 more
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